关键词: Angiofibroma Diagnostic challenge Epistaxis Functional endoscopic sinus surgery Plasmacytoma

来  源:   DOI:10.1016/j.radcr.2024.03.050   PDF(Pubmed)

Abstract:
Extramedullary plasmacytoma (EMP) is an uncommon tumor marked by the monoclonal growth of plasma cells without the characteristics of multiple myeloma. EMP represents 3% of all plasma cell tumors. An 89-year-old male patient with hypertension was admitted to our tertiary care hospital with uncontrolled unilateral epistaxis. After a year and a half of recurring epistaxis, the patient\'s bleeding became more frequent and could no longer be controlled with nasal packing. Angiofibroma was suspected as the initial differential diagnosis, and angiofibroma embolization was performed. The patient experienced difficulty swallowing and slurred speech and was diagnosed with an ischemic stroke. However, antiplatelet and tranexamic acid medications were contraindicated due to bleeding risks. The patient underwent functional endoscopic sinus surgery, and unexpectedly, histology results revealed a plasmacytoma. After surgery, the patient remained stable and was discharged for further management.
摘要:
髓外浆细胞瘤(EMP)是一种罕见的肿瘤,其特征是浆细胞的单克隆生长,而没有多发性骨髓瘤的特征。EMP占所有浆细胞肿瘤的3%。一名89岁的男性高血压患者因单侧鼻出血不受控制而入院。经过一年半的反复发作,患者的出血变得更加频繁,不能再通过鼻腔填塞来控制。怀疑血管纤维瘤是最初的鉴别诊断,并进行血管纤维瘤栓塞术。患者出现吞咽困难和言语不清,并被诊断为缺血性中风。然而,抗血小板药物和氨甲环酸药物因出血风险而被禁用.患者接受了功能性内窥镜鼻窦手术,出乎意料的是,组织学结果显示浆细胞瘤。手术后,患者保持稳定,出院接受进一步治疗.
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