关键词: PSD depression network meta-analysis stroke systematic reviews

来  源:   DOI:10.3389/fneur.2024.1376336   PDF(Pubmed)

Abstract:
UNASSIGNED: To investigate the effects of nonpharmacological interventions (NPIs) on poststroke depression (PSD) in stroke patients.
UNASSIGNED: Computer searches were conducted on the PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), and Wanfang databases from their establishment to December 2023. The selection was made using the inclusion and exclusion criteria, and 40 articles were included to compare the effects of the 17 NPIs on patients with PSD.
UNASSIGNED: Forty studies involving seventeen interventions were included. The network findings indicated that compared with conventional therapy (COT), superior PSD improvement was observed for cognitive behavioral therapy (CBT) + acupoint acupuncture (CBTA) (mean difference [MD], -4.25; 95% CI, -5.85 to -2.65), team positive psychotherapy (MD, -4.05; 95% CI, -5.53 to -2.58), music therapy (MT) + positive psychological intervention (MD, -2.25; 95% CI, -3.65 to -0.85), CBT (MD, -1.52; 95% CI, -2.05 to -0.99), mindfulness-based stress reduction (MD, -1.14; 95% CI, -2.14 to -0.14), MT (MD, -0.95; 95% CI, -1.39 to -0.52), acupoint acupuncture + MT (AAMT) (MD, -0.69; 95% CI, -1.25 to -0.14). Furthermore, CBT (MD, -3.87; 95% CI, -4.57 to -3.17), AAMT (MD, -1.02; 95% CI, -1.41 to -0.62), acupressure + MT (MD, -0.91; 95% CI, -1.27 to -0.54), and narrative care + acupressure (MD, -0.74; 95% CI, -1.19 to -0.29) demonstrated superior Pittsburgh Sleep Quality Index (PSQI) improvement compared with COT.
UNASSIGNED: Evidence from systematic reviews and meta-analyses suggests that CBTA improves depression in patients with PSD. Moreover, CBT improves sleep in these patients. Additional randomized controlled trials are required to further investigate the efficacy and mechanisms of these interventions.
摘要:
研究非药物干预(NPI)对卒中患者卒中后抑郁(PSD)的影响。
在PubMed上进行了计算机搜索,Embase,科克伦图书馆,WebofScience,中国国家知识基础设施(CNKI),中国科技期刊数据库(VIP),和万方数据库从成立到2023年12月。使用纳入和排除标准进行选择,纳入40篇文章,比较17种NPI对PSD患者的影响。
包括涉及17项干预措施的40项研究。网络研究结果表明,与常规治疗(COT)相比,认知行为疗法(CBT)+穴位针刺(CBTA)观察到明显的PSD改善(平均差异[MD],-4.25;95%CI,-5.85至-2.65),团队积极心理治疗(MD,-4.05;95%CI,-5.53至-2.58),音乐疗法(MT)+积极心理干预(MD,-2.25;95%CI,-3.65至-0.85),CBT(MD,-1.52;95%CI,-2.05至-0.99),基于正念的减压(MD,-1.14;95%CI,-2.14至-0.14),MT(MD,-0.95;95%CI,-1.39至-0.52),穴位针刺+MT(AAMT)(MD,-0.69;95%CI,-1.25至-0.14)。此外,CBT(MD,-3.87;95%CI,-4.57至-3.17),AAMT(MD,-1.02;95%CI,-1.41至-0.62),穴位按摩+MT(MD,-0.91;95%CI,-1.27至-0.54),和叙事护理+穴位按压(MD,-0.74;95%CI,-1.19至-0.29)与COT相比,匹兹堡睡眠质量指数(PSQI)改善。
系统评价和荟萃分析的证据表明,CBTA可改善PSD患者的抑郁。此外,CBT改善这些患者的睡眠。需要更多的随机对照试验来进一步研究这些干预措施的疗效和机制。
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