PDF(Pubmed)
Abstract：
UNASSIGNED: Malaria is a leading cause of death among children under 5 years of age in sub-Saharan Africa. The malaria vaccine is an important preventive measure introduced by the World Health Organization to reduce malaria and its associated mortality and morbidity. We aimed to assess the acceptance of the malaria vaccine among next of kin of children under 5 years of age in Gulu City, Northern Uganda.
UNASSIGNED: Between October and December 2023, we conducted a cross-sectional study in Pece-Laroo division, Gulu City, Uganda. Socio-demographic, vaccine profile and health system factors were collected. Multivariable logistic regression was performed using STATA 16 to determine factors associated with acceptance of the malaria vaccine among next of kin of children under 5 years.
UNASSIGNED: A total of 432 participants were enrolled. Of these, the majority were female (72.5%, n = 313) with most aged 30 years and above (51.2%, n = 221). Overall, 430 (99.5%) participants had good knowledge about malaria. The majority (91.4%, n = 395) had good acceptance of the malaria vaccine. Factors independently associated with acceptance of the malaria vaccine were knowing a child who died of malaria [adjusted prevalence ratio (aPR): 1.07, 95% confidence interval (CI): 1.01-1.13, p = 0.022] and preferring the injection route for a malaria vaccine (aPR: 1.1, 95% CI: 1.06-1.22, p < 0.001). All 395 participants with good knowledge of malaria had good acceptance of the malaria vaccine (p = 0.007).
UNASSIGNED: There was a high acceptance of the malaria vaccine in Laroo-Pece division, Gulu, Uganda. However, there is a need for further health education to achieve universal acceptability of the malaria vaccine in preparation for the malaria vaccine implementation program in Uganda.
UNASSIGNED: Between October and December 2023, we conducted a cross-sectional study in Pece-Laroo division, Gulu City, Uganda. Socio-demographic, vaccine profile and health system factors were collected. Multivariable logistic regression was performed using STATA 16 to determine factors associated with acceptance of the malaria vaccine among next of kin of children under 5 years.
UNASSIGNED: A total of 432 participants were enrolled. Of these, the majority were female (72.5%, n = 313) with most aged 30 years and above (51.2%, n = 221). Overall, 430 (99.5%) participants had good knowledge about malaria. The majority (91.4%, n = 395) had good acceptance of the malaria vaccine. Factors independently associated with acceptance of the malaria vaccine were knowing a child who died of malaria [adjusted prevalence ratio (aPR): 1.07, 95% confidence interval (CI): 1.01-1.13, p = 0.022] and preferring the injection route for a malaria vaccine (aPR: 1.1, 95% CI: 1.06-1.22, p < 0.001). All 395 participants with good knowledge of malaria had good acceptance of the malaria vaccine (p = 0.007).
UNASSIGNED: There was a high acceptance of the malaria vaccine in Laroo-Pece division, Gulu, Uganda. However, there is a need for further health education to achieve universal acceptability of the malaria vaccine in preparation for the malaria vaccine implementation program in Uganda.
摘要：
疟疾是撒哈拉以南非洲5岁以下儿童死亡的主要原因。疟疾疫苗是世界卫生组织为降低疟疾及其相关死亡率和发病率而推出的一项重要预防措施。我们旨在评估古鲁市5岁以下儿童近亲对疟疾疫苗的接受程度，乌干达北部。
■在2023年10月至12月之间，我们在Pece-Laroo部门进行了一项横断面研究，古鲁市,乌干达。社会人口学，收集疫苗概况和卫生系统因素。使用STATA16进行多变量逻辑回归，以确定与5岁以下儿童的近亲接受疟疾疫苗相关的因素。
■共有432名参与者注册。其中,大多数是女性(72.5%，n=313)，大多数年龄在30岁及以上(51.2%，n=221)。总的来说,430名（99.5%）参与者对疟疾有很好的了解。大多数（91.4%，n=395）对疟疾疫苗具有良好的接受度。与接受疟疾疫苗独立相关的因素是知道一个死于疟疾的儿童[调整后的患病率比（aPR）：1.07，95％置信区间（CI）：1.01-1.13，p=0.022]，并且更喜欢注射路径。疟疾疫苗（aPR：1.1，95％CI：1.06-1.22，p<0.001）。所有395名具有良好疟疾知识的参与者都接受了疟疾疫苗（p=0.007）。
■Laroo-Pece部门对疟疾疫苗的接受度很高，古鲁,乌干达。然而,需要进一步的健康教育，以实现疟疾疫苗的普遍接受，为乌干达的疟疾疫苗实施计划做准备。
■在2023年10月至12月之间，我们在Pece-Laroo部门进行了一项横断面研究，古鲁市,乌干达。社会人口学，收集疫苗概况和卫生系统因素。使用STATA16进行多变量逻辑回归，以确定与5岁以下儿童的近亲接受疟疾疫苗相关的因素。
■共有432名参与者注册。其中,大多数是女性(72.5%，n=313)，大多数年龄在30岁及以上(51.2%，n=221)。总的来说,430名（99.5%）参与者对疟疾有很好的了解。大多数（91.4%，n=395）对疟疾疫苗具有良好的接受度。与接受疟疾疫苗独立相关的因素是知道一个死于疟疾的儿童[调整后的患病率比（aPR）：1.07，95％置信区间（CI）：1.01-1.13，p=0.022]，并且更喜欢注射路径。疟疾疫苗（aPR：1.1，95％CI：1.06-1.22，p<0.001）。所有395名具有良好疟疾知识的参与者都接受了疟疾疫苗（p=0.007）。
■Laroo-Pece部门对疟疾疫苗的接受度很高，古鲁,乌干达。然而,需要进一步的健康教育，以实现疟疾疫苗的普遍接受，为乌干达的疟疾疫苗实施计划做准备。
