METHODS: Systematic literature review (Scopus and PubMed, up to October 11, 2023).
METHODS: All study designs.
METHODS: Organ recipients from patients on ECMO at the time of death.
METHODS: Outcome of organ donation from ECMO donors.
RESULTS: The search yielded 1,692 publications, with 20 studies ultimately included, comprising 147 donors and 360 organ donations. The most frequently donated organs were kidneys (68%, 244/360), followed by liver (24%, 85/360). In total, 98% (292/299) of recipients survived with a preserved graft function (92%, 319/347) until follow-up within a variable period of up to 3 years.
CONCLUSIONS: Organ transplantation from donors supported with ECMO at the time of death shows high graft and recipient survival. ECMO could be a suitable approach for expanding the donor pool, helping to alleviate the worldwide organ shortage.
方法:系统文献综述(Scopus和PubMed,截至2023年10月11日)。
方法:所有研究设计。
方法:在死亡时接受ECMO治疗的患者的器官接受者。
方法:来自ECMO捐献者的器官捐献结果。
结果:搜索产生了1,692种出版物,最终纳入了20项研究,包括147个捐赠者和360个器官捐赠。最常捐献的器官是肾脏(68%,244/360),其次是肝脏(24%,85/360)。总的来说,98%(292/299)的受体存活下来,移植物功能得到保留(92%,319/347),直到在长达3年的可变期限内进行随访。
结论:在死亡时用ECMO支持的供体的器官移植显示出较高的移植物和受体存活率。ECMO可能是扩大捐助池的合适方法,帮助缓解全球器官短缺。