Abstract：
OBJECTIVE: The mismatch between the demand for and supply of organs for transplantation is steadily growing. Various strategies have been incorporated to improve the availability of organs, including organ use from patients receiving extracorporeal membrane oxygenation (ECMO) at the time of death. However, there is no systematic evidence of the outcome of grafts from these donors.
METHODS: Systematic literature review (Scopus and PubMed, up to October 11, 2023).
METHODS: All study designs.
METHODS: Organ recipients from patients on ECMO at the time of death.
METHODS: Outcome of organ donation from ECMO donors.
RESULTS: The search yielded 1,692 publications, with 20 studies ultimately included, comprising 147 donors and 360 organ donations. The most frequently donated organs were kidneys (68%, 244/360), followed by liver (24%, 85/360). In total, 98% (292/299) of recipients survived with a preserved graft function (92%, 319/347) until follow-up within a variable period of up to 3 years.
CONCLUSIONS: Organ transplantation from donors supported with ECMO at the time of death shows high graft and recipient survival. ECMO could be a suitable approach for expanding the donor pool, helping to alleviate the worldwide organ shortage.
METHODS: Systematic literature review (Scopus and PubMed, up to October 11, 2023).
METHODS: All study designs.
METHODS: Organ recipients from patients on ECMO at the time of death.
METHODS: Outcome of organ donation from ECMO donors.
RESULTS: The search yielded 1,692 publications, with 20 studies ultimately included, comprising 147 donors and 360 organ donations. The most frequently donated organs were kidneys (68%, 244/360), followed by liver (24%, 85/360). In total, 98% (292/299) of recipients survived with a preserved graft function (92%, 319/347) until follow-up within a variable period of up to 3 years.
CONCLUSIONS: Organ transplantation from donors supported with ECMO at the time of death shows high graft and recipient survival. ECMO could be a suitable approach for expanding the donor pool, helping to alleviate the worldwide organ shortage.
摘要：
目的：移植器官的需求和供应之间的不匹配正在稳步增长。已经纳入了各种战略，以改善器官的可用性，包括死亡时接受体外膜氧合（ECMO）的患者的器官使用。然而,没有系统的证据表明这些捐赠者移植的结果.
方法：系统文献综述(Scopus和PubMed，截至2023年10月11日）。
方法：所有研究设计。
方法：在死亡时接受ECMO治疗的患者的器官接受者。
方法：来自ECMO捐献者的器官捐献结果。
结果：搜索产生了1,692种出版物，最终纳入了20项研究，包括147个捐赠者和360个器官捐赠。最常捐献的器官是肾脏（68%，244/360），其次是肝脏(24%，85/360)。总的来说,98%(292/299)的受体存活下来，移植物功能得到保留(92%，319/347），直到在长达3年的可变期限内进行随访。
结论：在死亡时用ECMO支持的供体的器官移植显示出较高的移植物和受体存活率。ECMO可能是扩大捐助池的合适方法，帮助缓解全球器官短缺。
方法：系统文献综述(Scopus和PubMed，截至2023年10月11日）。
方法：所有研究设计。
方法：在死亡时接受ECMO治疗的患者的器官接受者。
方法：来自ECMO捐献者的器官捐献结果。
结果：搜索产生了1,692种出版物，最终纳入了20项研究，包括147个捐赠者和360个器官捐赠。最常捐献的器官是肾脏（68%，244/360），其次是肝脏(24%，85/360)。总的来说,98%(292/299)的受体存活下来，移植物功能得到保留(92%，319/347），直到在长达3年的可变期限内进行随访。
结论：在死亡时用ECMO支持的供体的器官移植显示出较高的移植物和受体存活率。ECMO可能是扩大捐助池的合适方法，帮助缓解全球器官短缺。
