PDF(Pubmed)
Abstract：
UNASSIGNED: In this study, we investigated the effect of various oxygen therapy regimens on oxygenation in patients with acute type A aortic dissection (AAD).
UNASSIGNED: A quasi-randomized controlled trial was conducted, in which patients with AAD hospitalized for surgery from June to September 2021 were assigned to the control group (patients received conventional oxygen therapy after postoperative mechanical ventilation, weaning, and extubation) and those who were admitted from October to December 2021 were assigned to the observation group [patients underwent optimally adjusted therapy based on the treatment of the control group, which mainly included prioritized elevation of positive end-expiratory pressure (PEEP) and restricted use of the fraction of inspired oxygen (FiO2)].The postoperative oxygenation index, blood gas analysis, and duration of mechanical ventilation were compared between the two groups.
UNASSIGNED: There were significant differences in oxygenation observed at 2 h postoperatively between the groups. 12, 24, and 72 h postoperatively, the oxygenation index varied significantly between the two groups. There were statistically significant differences in the time effects of the oxygenation index and PaO2 between the two groups, as well as significant differences in the length of stay in the intensive care unit.
UNASSIGNED: For the postoperative care of patients with AAD, it is suggested that the minimum FiO2 required for oxygenation of patients be maintained. In addition, it is possible to enhance PEEP as a priority when PaO2 is low.
UNASSIGNED: A quasi-randomized controlled trial was conducted, in which patients with AAD hospitalized for surgery from June to September 2021 were assigned to the control group (patients received conventional oxygen therapy after postoperative mechanical ventilation, weaning, and extubation) and those who were admitted from October to December 2021 were assigned to the observation group [patients underwent optimally adjusted therapy based on the treatment of the control group, which mainly included prioritized elevation of positive end-expiratory pressure (PEEP) and restricted use of the fraction of inspired oxygen (FiO2)].The postoperative oxygenation index, blood gas analysis, and duration of mechanical ventilation were compared between the two groups.
UNASSIGNED: There were significant differences in oxygenation observed at 2 h postoperatively between the groups. 12, 24, and 72 h postoperatively, the oxygenation index varied significantly between the two groups. There were statistically significant differences in the time effects of the oxygenation index and PaO2 between the two groups, as well as significant differences in the length of stay in the intensive care unit.
UNASSIGNED: For the postoperative care of patients with AAD, it is suggested that the minimum FiO2 required for oxygenation of patients be maintained. In addition, it is possible to enhance PEEP as a priority when PaO2 is low.
摘要：
■在这项研究中，我们研究了不同氧疗方案对急性A型主动脉夹层(AAD)患者氧合的影响.
■进行了一项准随机对照试验，其中2021年6月至9月住院手术的AAD患者被分配到对照组（患者在术后机械通气后接受常规氧疗，断奶,和拔管）以及2021年10月至12月入院的患者被分配到观察组[患者在对照组治疗的基础上接受了最佳调整治疗，主要包括优先提高呼气末正压（PEEP）和限制使用吸入氧气分数（FiO2）]。术后氧合指数,血气分析,比较两组机械通气时间。
■两组在术后2小时观察到的氧合存在显著差异。术后12、24和72小时，两组的氧合指数差异显著.两组氧合指数和PaO2的时间效应差异有统计学意义。以及在重症监护病房住院时间的显着差异。
■对于AAD患者的术后护理，建议维持患者氧合所需的最低FiO2。此外,当PaO2较低时,可以优先提高PEEP。
■进行了一项准随机对照试验，其中2021年6月至9月住院手术的AAD患者被分配到对照组（患者在术后机械通气后接受常规氧疗，断奶,和拔管）以及2021年10月至12月入院的患者被分配到观察组[患者在对照组治疗的基础上接受了最佳调整治疗，主要包括优先提高呼气末正压（PEEP）和限制使用吸入氧气分数（FiO2）]。术后氧合指数,血气分析,比较两组机械通气时间。
■两组在术后2小时观察到的氧合存在显著差异。术后12、24和72小时，两组的氧合指数差异显著.两组氧合指数和PaO2的时间效应差异有统计学意义。以及在重症监护病房住院时间的显着差异。
■对于AAD患者的术后护理，建议维持患者氧合所需的最低FiO2。此外,当PaO2较低时,可以优先提高PEEP。
