PDF(Pubmed)
Abstract：
Immune thrombocytopenic purpura (ITP) is a hematologic condition characterized by decreased circulating platelets, resulting in bruising, bleeding gums, and internal bleeding. This disorder can be categorized into two primary forms based on the duration of symptoms and underlying causes. Acute ITP primarily affects young children, typically between the ages of two and six, but it can also impact older children and adults. Viral infections like chickenpox, respiratory infections, or gastroenteritis often precede it. Acute ITP manifests suddenly and lasts for a short period, typically less than six months and sometimes only a few weeks. On the other hand, chronic ITP primarily affects adults but can occur at any age, including childhood and adolescence. The main characteristic of chronic ITP is the persistence of symptoms for more than six months. It can be either idiopathic (primary), with no discernible etiologic cause, or secondary to various conditions such as autoimmune diseases (e.g., systemic lupus erythematosus), viral infections (e.g., human immunodeficiency virus (HIV), hepatitis C virus (HCV)), certain malignancies (e.g., chronic lymphocytic leukemia), or drug reactions. This case report presents the management of a 36-year-old African American female diagnosed with ITP associated with systemic lupus erythematosus, Helicobacter (H.) pylori, and hepatitis B infection.
摘要：
免疫性血小板减少性紫癜（ITP）是一种以循环血小板减少为特征的血液学疾病，导致瘀伤，牙龈出血,和内出血。根据症状的持续时间和潜在原因，这种疾病可以分为两种主要形式。急性ITP主要影响幼儿，通常在2到6岁之间，但它也会影响年龄较大的儿童和成人。病毒感染像水痘,呼吸道感染,或者胃肠炎通常先于它。急性ITP表现突然并持续一小段时间,通常少于六个月，有时只有几周。另一方面,慢性ITP主要影响成年人，但可以发生在任何年龄，包括童年和青春期。慢性ITP的主要特征是症状持续超过六个月。它可以是特发性（原发性），没有明显的病因，或继发于各种疾病，如自身免疫性疾病(例如，系统性红斑狼疮)，病毒感染(例如，人类免疫缺陷病毒（HIV），丙型肝炎病毒（HCV），某些恶性肿瘤(例如，慢性淋巴细胞白血病），或药物反应。该病例报告介绍了一名36岁的非洲裔美国女性的治疗，该女性被诊断为与系统性红斑狼疮相关的ITP。螺杆菌(H.)pylori,和乙型肝炎感染。
