PDF(Pubmed)
Abstract：
Guillain-Barré syndrome (GBS) is a rare postoperative complication that is sometimes characterized by serious motor weakness and prolonged weaning from mechanical ventilation. Although the exact nature of the relationship between GBS and the surgical procedure is still unclear, there is a clear increased incidence of GBS in post-surgical patients compared to non-surgical patients. GBS after surgery is unique in several ways. The course of post-surgical GBS unfolds more rapidly than in other situations where GBS develops, the condition is often more severe, and respiratory muscles are more commonly involved. Prompt diagnosis and appropriate treatment are essential, and the condition can worsen if treated inappropriately. Postoperative sedation, intubation, and restraint use make the diagnosis of GBS difficult, as the onset of symptoms of weakness or numbness in those contexts are not obvious. GBS is often misdiagnosed, being attributed to other postoperative complications, and subsequently mishandled. The lack of relevant information further obscures the clinical picture. We sought to better understand post-surgical GBS by performing an analysis of the relevant literature, focusing on clearly documenting the clinical characteristics, diagnosis, and management of GBS that emerges following surgery. We underscore the importance of physicians being aware of the possibility of GBS after major surgery and of performing a variety of laboratory clinical investigations early on in suspected cases.
摘要：
格林-巴利综合征（GBS）是一种罕见的术后并发症，有时以严重的运动无力和机械通气的长时间断奶为特征。尽管GBS与外科手术之间关系的确切性质尚不清楚，与非手术患者相比,手术后患者的GBS发生率明显增加.手术后的GBS在几个方面是独特的。术后GBS的过程比GBS发展的其他情况下更快地展开，情况通常更严重，呼吸肌更常见。及时的诊断和适当的治疗至关重要，如果治疗不当，病情会恶化。术后镇静,插管,限制使用使GBS的诊断变得困难，在这些情况下，虚弱或麻木症状的发作并不明显。GBS常被误诊,归因于其他术后并发症，随后处理不当。相关信息的缺乏进一步掩盖了临床情况。我们试图通过分析相关文献来更好地理解手术后GBS，专注于清楚地记录临床特征，诊断,以及手术后出现的GBS的管理。我们强调了医生意识到大手术后GBS的可能性以及在疑似病例中早期进行各种实验室临床研究的重要性。
