PDF(Pubmed)
Abstract：
UNASSIGNED: Many data were published about Long-Covid prevalence, very few about the findings of new cardiac alterations (NCA) in COVID-19-recovered people. ARCA-post-COVID is an observational study designed to investigate the prevalence of NCA in patients recovered from Covid-19.Methods: from June 2020 to December 2022, we enrolled 502 patients with a positive nasopharyngeal swab for SARS-CoV2 and a subsequent negative one. We performed anamnesis, lab-test, and routine cardiological tests (ECG, Holter, TTE).
UNASSIGNED: The median age was 56 years (IQR 44-67); women were 52.19%; in the acute phase 24.1% of patients were treated in a medical department, 7.2% in the ICU and the others at home. At the visit, 389 patients (77.49%) complained of a broad range of symptoms. We reported patients\' characteristics according to the course of the disease and the persistence of symptoms. NCA were found in 138 patients (27.49%): among them 60 cases (11.95%) of pericardial effusion. Patients with NCA were older (median 60y, IQR: 47-72, vs median 56y, IQR 42-65), had a higher prevalence of smokers (27% vs 17%; p0.014), CAD (11% vs 6%; p0.048) and stroke/TIA (3.6% vs 0.3%; p0.002) and a lower prevalence of hypercholesterolemia (18% vs 30%; p0.007). The prevalence of NCA seems constant with different subtypes of the virus.
UNASSIGNED: the prevalence of NCA in patients who recovered from COVID-19 is high and constant since the beginning of the pandemic; it is predictable based on hospitalization and long-lasting symptoms (9.64%-42.52%). Patients with one of these characteristics should undergo cardiological screening.
UNASSIGNED: The median age was 56 years (IQR 44-67); women were 52.19%; in the acute phase 24.1% of patients were treated in a medical department, 7.2% in the ICU and the others at home. At the visit, 389 patients (77.49%) complained of a broad range of symptoms. We reported patients\' characteristics according to the course of the disease and the persistence of symptoms. NCA were found in 138 patients (27.49%): among them 60 cases (11.95%) of pericardial effusion. Patients with NCA were older (median 60y, IQR: 47-72, vs median 56y, IQR 42-65), had a higher prevalence of smokers (27% vs 17%; p0.014), CAD (11% vs 6%; p0.048) and stroke/TIA (3.6% vs 0.3%; p0.002) and a lower prevalence of hypercholesterolemia (18% vs 30%; p0.007). The prevalence of NCA seems constant with different subtypes of the virus.
UNASSIGNED: the prevalence of NCA in patients who recovered from COVID-19 is high and constant since the beginning of the pandemic; it is predictable based on hospitalization and long-lasting symptoms (9.64%-42.52%). Patients with one of these characteristics should undergo cardiological screening.
摘要：
■发表了许多关于长型Covid患病率的数据，关于COVID-19康复患者新的心脏改变(NCA)的发现很少。ARCA-post-COVID是一项观察性研究，旨在调查从Covid-19康复的患者中NCA的患病率。方法：从2020年6月至2022年12月，我们招募了502例SARS-CoV2鼻咽拭子阳性和随后阴性的患者。我们做了回忆，实验室测试,和常规心脏检查(心电图，Holter,TTE）。
■中位年龄为56岁（IQR44-67）；女性为52.19％；在急性期，有24.1％的患者在医疗部门接受治疗，在ICU和其他人在家里的7.2％。参观时,389例患者（77.49%）主诉广泛的症状。我们根据病程和症状的持续性报告了患者的特征。138例患者中发现NCA（27.49％）：其中心包积液60例（11.95％）。NCA患者年龄较大(中位数60岁，IQR：47-72，相对于中位数56y，IQR42-65），吸烟者的患病率较高（27％vs17％；p0.014），CAD(11%vs6%;p0.048)和卒中/TIA(3.6%vs0.3%;p0.002),高胆固醇血症患病率较低(18%vs30%;p0.007)。NCA的流行率似乎在病毒的不同亚型下是恒定的。
■自大流行开始以来，从COVID-19康复的患者中NCA的患病率很高且恒定；根据住院和长期症状（9.64％-42.52％），这是可以预测的。具有这些特征之一的患者应进行心脏筛查。
■中位年龄为56岁（IQR44-67）；女性为52.19％；在急性期，有24.1％的患者在医疗部门接受治疗，在ICU和其他人在家里的7.2％。参观时,389例患者（77.49%）主诉广泛的症状。我们根据病程和症状的持续性报告了患者的特征。138例患者中发现NCA（27.49％）：其中心包积液60例（11.95％）。NCA患者年龄较大(中位数60岁，IQR：47-72，相对于中位数56y，IQR42-65），吸烟者的患病率较高（27％vs17％；p0.014），CAD(11%vs6%;p0.048)和卒中/TIA(3.6%vs0.3%;p0.002),高胆固醇血症患病率较低(18%vs30%;p0.007)。NCA的流行率似乎在病毒的不同亚型下是恒定的。
■自大流行开始以来，从COVID-19康复的患者中NCA的患病率很高且恒定；根据住院和长期症状（9.64％-42.52％），这是可以预测的。具有这些特征之一的患者应进行心脏筛查。
