PDF(Pubmed)
Abstract：
BACKGROUND: Image-guided adaptive brachytherapy (IGABT) demonstrates an excellent local control rate and low toxicity while treating cervical cancer. For intracavitary/interstitial (IC/IS) brachytherapy (BT), several applicators are commercially available. Venezia (Elekta, Sweden), an advanced gynecological applicator, is designed for IC/IS BT for treating locally advanced cervical cancer. There are two types of interstitial needles for the Venezia applicator: the round needle and sharp needle. Generally, a round needle is safer because it has less risk of damaging the organ at risk than a sharp needle. However, there is currently no evidence to suggest that a round needle is better than a sharp needle for the Venezia applicator in IC/IS BT. Herein, we documented our experience of using both round and sharp needles with the Venezia applicator in IC/IS BT for cervical cancer.
METHODS: A 71-year-old woman was diagnosed with clinical stage T2bN0M0 and the International Federation of Gynecology and Obstetrics stage IIB cervical squamous cell carcinoma. Definitive therapy, including a high-dose-rate BT boost, was planned using a round needle with the Venezia applicator in IC/IS BT. After inserting four interstitial round needles during the first and second BT sessions, an unexpectedly large gap (1.5 cm) was detected between the cervix and ovoid. We therefore used a sharp needle with the Venezia applicator for IC/IS BT during the third and fourth BT sessions. Three sharp needles were firmly inserted during the third and fourth BT sessions.
CONCLUSIONS: The study findings suggest that the interstitial round needle should not be used for cervical cancer patients undergoing IC/IS BT using the Venezia applicator.
METHODS: A 71-year-old woman was diagnosed with clinical stage T2bN0M0 and the International Federation of Gynecology and Obstetrics stage IIB cervical squamous cell carcinoma. Definitive therapy, including a high-dose-rate BT boost, was planned using a round needle with the Venezia applicator in IC/IS BT. After inserting four interstitial round needles during the first and second BT sessions, an unexpectedly large gap (1.5 cm) was detected between the cervix and ovoid. We therefore used a sharp needle with the Venezia applicator for IC/IS BT during the third and fourth BT sessions. Three sharp needles were firmly inserted during the third and fourth BT sessions.
CONCLUSIONS: The study findings suggest that the interstitial round needle should not be used for cervical cancer patients undergoing IC/IS BT using the Venezia applicator.
摘要：
背景：图像引导自适应近距离放射治疗（IGABT）在治疗宫颈癌时显示出出色的局部控制率和低毒性。对于腔内/间质（IC/IS）近距离放射治疗（BT），几个施药器是商业上可用的。威尼斯(Elekta,瑞典),先进的妇科涂药器,设计用于IC/ISBT治疗局部晚期宫颈癌。Venezia涂药器有两种类型的间隙针：圆形针和锋利针。一般来说,圆针更安全，因为它比锋利的针损伤危险器官的风险更小。然而,目前尚无证据表明,对于IC/ISBT中的Venezia涂药器,圆针优于尖针.在这里，我们记录了我们在IC/ISBT中使用Venezia涂药器同时使用圆形和锋利针头治疗宫颈癌的经验。
方法：一名71岁女性被诊断为临床分期T2bN0M0和国际妇产科联合会IIB期宫颈鳞状细胞癌。明确治疗，包括高剂量率的BT增强，计划在IC/ISBT中使用带有Venezia涂抹器的圆针。在第一次和第二次BT期间插入四根间质圆针后，在子宫颈和卵圆形之间检测到一个出乎意料的大间隙（1.5厘米）。因此，在第三次和第四次BT会议期间，我们将锋利的针头与Venezia涂药器一起用于IC/ISBT。在第三次和第四次BT会议期间，三根锋利的针被牢固地插入。
结论：研究结果表明，对于使用Venezia涂药器进行IC/ISBT的宫颈癌患者，不应使用间质圆针。
方法：一名71岁女性被诊断为临床分期T2bN0M0和国际妇产科联合会IIB期宫颈鳞状细胞癌。明确治疗，包括高剂量率的BT增强，计划在IC/ISBT中使用带有Venezia涂抹器的圆针。在第一次和第二次BT期间插入四根间质圆针后，在子宫颈和卵圆形之间检测到一个出乎意料的大间隙（1.5厘米）。因此，在第三次和第四次BT会议期间，我们将锋利的针头与Venezia涂药器一起用于IC/ISBT。在第三次和第四次BT会议期间，三根锋利的针被牢固地插入。
结论：研究结果表明，对于使用Venezia涂药器进行IC/ISBT的宫颈癌患者，不应使用间质圆针。
