PDF(Pubmed)
Abstract：
We analyzed chemoport insertion procedures to evaluate infectious morbidity and factors causing infection. This single-center retrospective study included 1690 cases of chemoport implantation between January 2017 and December 2020. Overall, chemoports were inserted in 1582 patients. The average duration of chemoport use was 481 days (range 1-1794, median 309). Infections occurred in 80 cases (4.7%), with 0.098 per 1000 catheter-days. Among the 80 cases in which chemoports were removed because of suspected infection, bacteria were identified in 48 (60%). Significantly more cases of left internal jugular vein punctures were noted in the infected group (15 [18.8%] vs. 147 [9.1%]; p = 0.004). Pulmonary embolism was significantly different between the infection groups (3 [3.8%] vs. 19 (1.2%), p = 0.048). The hazard ratio was 2.259 (95% confidence interval [CI] 1.288-3.962) for the left internal jugular vein, 3.393 (95% CI 1.069-10.765) for pulmonary embolism, and 0.488 (95% CI 0.244-0.977) for chronic obstructive pulmonary disease. Using the right internal jugular vein rather than the left internal jugular vein when performing chemoport insertion might reduce subsequent infections.
摘要：
我们分析了放化疗程序，以评估感染发病率和引起感染的因素。这项单中心回顾性研究包括2017年1月至2020年12月期间的1690例Chemoport植入病例。总的来说,在1582名患者中插入了化学端口。化疗的平均使用时间为481天（范围为1-1794，中位数为309天）。感染80例（4.7%），每1000个导管天0.098。在80例因疑似感染而移除趋化因子的病例中，细菌被鉴定为48（60％）。在感染组中，左颈内静脉穿刺的病例明显增多（15[18.8％]vs.147[9.1%]；p=0.004）。肺栓塞在感染组之间有显着差异（3[3.8％]vs.19（1.2%），p=0.048)。左颈内静脉的风险比为2.259（95%置信区间[CI]1.288-3.962），3.393（95%CI1.069-10.765）用于肺栓塞，慢性阻塞性肺疾病为0.488（95%CI0.244-0.977）。使用右颈内静脉而不是左颈内静脉时进行化疗插入可能会减少随后的感染。
