METHODS: 207 lung cancer patients who underwent lobectomy at Yunnan Cancer Hospital between January 2020 and December 2020. All patients had stage IA primary lung cancer and were performed by the same surgical team. And computed tomography examinations were performed before and 1 y postoperatively. Based on computed tomography images, the volume of each lung lobe was measured using computer software and manual, the radiological lung weight was calculated. And multiple linear regressions were used to analyze the factors related to the increase in postoperative lung weight.
RESULTS: One year after lobectomy, the radiological lung weight increased by an average of 112.4 ± 20.8%. Smoking history, number of resected lung segments, preoperative low attenuation volume, intraoperative arterial oxygen partial pressure/fraction of inspired oxygen ratio and postoperative visual analog scale scores at 48 h were significantly associated with postoperative radiological lung weight gain.
CONCLUSIONS: Our results suggest that CLG have occurred after lobectomy in adults. In addition, anesthetists should maintain high arterial oxygen partial pressure/fraction of inspired oxygen ratio during one-lung ventilation and improve acute postoperative pain to benefit CLG.
方法:207例2020年1月至2020年12月在云南省肿瘤医院行肺叶切除术的肺癌患者。所有患者均为IA期原发性肺癌,由同一手术团队进行。术前和术后1年进行计算机断层扫描检查。根据计算机断层扫描图像,使用计算机软件和手册测量每个肺叶的体积,计算放射性肺重量.并采用多元线性回归分析术后肺体重增加的相关因素。
结果:肺叶切除术后一年,放射性肺重量平均增加112.4±20.8%。吸烟史,切除的肺段数,术前低衰减量,术中动脉血氧分压/吸入氧分压比值和术后48h视觉模拟量表评分与术后放射性肺增重显著相关.
结论:我们的结果表明,成人肺叶切除术后发生CLG。此外,麻醉师应在单肺通气期间维持高动脉氧分压/吸入氧分压比,并改善急性术后疼痛,以使CLG受益.