关键词: Fracture liaison service adherence bisphosphonate denosumab osteoporosis re-fracture

Mesh : Humans Osteoporosis / therapy drug therapy Bone Density Conservation Agents / therapeutic use Follow-Up Studies Retrospective Studies Osteoporotic Fractures / diagnosis epidemiology prevention & control Pain / drug therapy

来  源:   DOI:10.1177/03000605241245280   PDF(Pubmed)

Abstract:
OBJECTIVE: We established an orthopedic ward fracture liaison services (OWFLS) model and evaluated its role in improving detection rates of bone metabolic markers, treatment rates, and long-term treatability.
METHODS: This observational retrospective cohort study included 120 patients aged >50 years hospitalized for primary osteoporotic fracture from January 2018 to January 2019 (group A: not included in OWFLS). Group B (included in OWFLS) comprised 120 patients from February 2019 to February 2020. We compared rates of bone metabolic index testing, treatment, and adherence; symptomatic improvement; and recurrent fracture between groups.
RESULTS: Rates of bone metabolism index testing (50% vs. 0%) and medication use (94.2% vs. 64.2%) were significantly higher after OWFLS implementation. There was no significant difference in adherence rates at 3 months between groups (97.3% vs. 93.5%). Adherence rates at 1 and 3 years were better in group B than A (73.5% vs. 51.9%; 57.5% vs. 26%, respectively). Recurrence of bone pain at 1 and 3 years was significantly lower in group B than A (20.4% vs. 46.8%; 45.1% vs. 76.6%, respectively).
CONCLUSIONS: OWFLS improved the detection rate of bone metabolism indicators, treatment rate, and patient adherence and reduced recurrence of bone pain. OWFLS may be suitable for settings lacking human resources.
摘要:
目的:我们建立了骨科病房骨折联络服务(OWFLS)模型,并评估了其在提高骨代谢标志物检出率中的作用,治疗率,和长期治疗。
方法:本观察性回顾性队列研究纳入了2018年1月至2019年1月因原发性骨质疏松性骨折住院的120例年龄>50岁的患者(A组:未纳入OWFLS)。B组(包括OWFLS)包括2019年2月至2020年2月的120名患者。我们比较了骨代谢指标测试的比率,治疗,和依从性;症状改善;组间复发性骨折。
结果:骨代谢指标测试率(50%vs.0%)和药物使用(94.2%vs.64.2%)显著高于OWFLS实施后。组间3个月的依从率无显著差异(97.3%vs.93.5%)。B组1年和3年的依从率优于A组(73.5%vs.51.9%;57.5%与26%,分别)。B组1年和3年的骨痛复发明显低于A组(20.4%vs.46.8%;45.1%与76.6%,分别)。
结论:OWFLS提高了骨代谢指标的检出率,治疗率,和患者的依从性和减少骨痛的复发。OWFLS可能适用于缺乏人力资源的环境。
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