Mesh : Female Humans Uterine Cervical Neoplasms / diagnosis Cross-Sectional Studies Ethiopia / epidemiology Precancerous Conditions / pathology Carcinoma, Squamous Cell / epidemiology pathology Squamous Intraepithelial Lesions Uterine Cervical Dysplasia / diagnosis

来  源:   DOI:10.1371/journal.pone.0301559   PDF(Pubmed)

Abstract:
BACKGROUND: The cervix is the lower portion of the uterus, which connects this organ to the vagina through the endocervical canal.
OBJECTIVE: This study aimed to determine the histopathologic patterns and factors associated with cervical lesions at Jimma Medical Center from September 12, 2017, to September 12, 2019.
METHODS: A 2-year facility-based cross-sectional study was conducted from May 1 to June 30, 2020.
RESULTS: In this study, cervical cancer was the most common (71%) cause of cervical lesions. Squamous cell carcinoma was the most frequent cervical cancer diagnosed during the study, accounting for 96.4% of 331 cancerous cases, followed by adenocarcinoma (3.3%). High-grade squamous intraepithelial lesions were the most frequently diagnosed precancerous lesions, accounting for 68.4% of cases. Endocervical polyps were the most commonly diagnosed benign lesions, accounting for 59.3% of cases.
CONCLUSIONS: The maximum age distribution of cervical lesions was in the 41-50-year age range. Squamous cell carcinoma was the most frequent type of cervical cancer. High-grade squamous intraepithelial lesions were the most frequently diagnosed precancerous cervical lesions. The most common benign cervical lesions were endocervical polyps.
CONCLUSIONS: We recommend educating the community to improve health-seeking behavior and on possible preventive strategies for cervical cancer.
摘要:
背景:子宫颈是子宫的下部,通过宫颈管将这个器官连接到阴道。
目的:本研究旨在确定2017年9月12日至2019年9月12日在Jimma医学中心与宫颈病变相关的组织病理学模式和因素。
方法:一项为期2年的基于设施的横断面研究于2020年5月1日至6月30日进行。
结果:在这项研究中,宫颈癌是最常见的(71%)宫颈病变的原因。鳞状细胞癌是研究期间诊断出的最常见的宫颈癌,占331例癌症病例的96.4%,其次是腺癌(3.3%)。高度鳞状上皮内病变是最常见的癌前病变,占病例的68.4%。宫颈息肉是最常见的良性病变,占病例的59.3%。
结论:宫颈病变的最大年龄分布在41-50岁之间。鳞状细胞癌是最常见的宫颈癌类型。高度鳞状上皮内病变是最常见的宫颈癌前病变。最常见的良性宫颈病变是宫颈管息肉。
结论:我们建议对社区进行教育,以改善寻求健康的行为和可能的宫颈癌预防策略。
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