To compare blood and peritoneal lactate concentrations in a population of mares within 36 h post-partum, report a normal reference range and identify any impact of retained foetal membranes (RFMs).
This is a retrospective study evaluating healthy mares from which blood and peritoneal samples had been obtained within 36 h of parturition. Exclusion criteria included signs of abdominal pain within this period. Data was interrogated for normality using a Shapiro-Wilk test. Wilcoxon signed-rank test and Bland-Altman analysis were used to compare blood and peritoneal lactate concentrations. Linear regression was used to compare age and breed data with peritoneal lactate concentrations. Significance was defined as p < 0.05.
Forty mares met the inclusion criteria. Mean age was 12.6 ± 4.1 years, and most mares were multiparous (65%). Peritoneal lactate ((1.2 (IQR = 0.9-1.6) mmol/L) was increased compared to blood lactate concentration (0.7 (IQR = 0-1.1)mmol/L; p < 0.001). Plasma total protein (TP) concentrations were 68 (IQR = 64-74) g/L and peritoneal protein concentrations 8 (IQR = 4-9.7) g/L. Six mares developed RFM. The median fold-increase in peritoneal lactate concentration compared to blood lactate concentration was 0.9 (IQR: 0.01-1.7; range: 0-2.5). The reference range for peritoneal fluid lactate concentration was 0-2.5 mmol/L.
Peritoneal lactate concentrations in healthy post-partum mares remained within the normal reference range and were not influenced by RFM or parturition. Increased peritoneal lactate in this group warrants further investigation.
目的:比较母马在产后36小时内的血液和腹膜乳酸浓度,报告正常参考范围,并确定保留的胎膜(RFM)的任何影响。
方法:这是一项回顾性研究,评估在分娩后36小时内获得血液和腹膜样本的健康母马。排除标准包括在此期间的腹痛体征。使用Shapiro-Wilk检验询问数据的正常性。使用Wilcoxon符号秩检验和Bland-Altman分析比较血液和腹膜乳酸浓度。线性回归用于比较年龄和品种数据与腹膜乳酸浓度。显著性定义为p<0.05。
结果:40匹母马符合纳入标准。平均年龄为12.6±4.1岁,大多数母马是经产的(65%)。与血乳酸浓度(0.7(IQR=0-1.1)mmol/L;p<0.001)相比,腹膜乳酸((1.2(IQR=0.9-1.6)mmol/L)增加。血浆总蛋白(TP)浓度为68(IQR=64-74)g/L,腹膜蛋白浓度为8(IQR=4-9.7)g/L。六匹母马开发了RFM。与血乳酸浓度相比,腹膜乳酸浓度的中位倍数增加为0.9(IQR:0.01-1.7;范围:0-2.5)。腹腔液乳酸浓度的参考范围为0-2.5mmol/L。
结论:健康产后母马的腹膜乳酸浓度保持在正常参考范围内,不受RFM或分娩的影响。该组中腹膜乳酸的增加值得进一步研究。