PDF(Pubmed)
Abstract：
Peritoneal fluid lactate concentration is an important diagnostic tool in horses with abdominal pain. Information on peritoneal lactate concentrations is lacking following parturition in the mare.
To compare blood and peritoneal lactate concentrations in a population of mares within 36 h post-partum, report a normal reference range and identify any impact of retained foetal membranes (RFMs).
This is a retrospective study evaluating healthy mares from which blood and peritoneal samples had been obtained within 36 h of parturition. Exclusion criteria included signs of abdominal pain within this period. Data was interrogated for normality using a Shapiro-Wilk test. Wilcoxon signed-rank test and Bland-Altman analysis were used to compare blood and peritoneal lactate concentrations. Linear regression was used to compare age and breed data with peritoneal lactate concentrations. Significance was defined as p < 0.05.
Forty mares met the inclusion criteria. Mean age was 12.6 ± 4.1 years, and most mares were multiparous (65%). Peritoneal lactate ((1.2 (IQR = 0.9-1.6) mmol/L) was increased compared to blood lactate concentration (0.7 (IQR = 0-1.1)mmol/L; p < 0.001). Plasma total protein (TP) concentrations were 68 (IQR = 64-74) g/L and peritoneal protein concentrations 8 (IQR = 4-9.7) g/L. Six mares developed RFM. The median fold-increase in peritoneal lactate concentration compared to blood lactate concentration was 0.9 (IQR: 0.01-1.7; range: 0-2.5). The reference range for peritoneal fluid lactate concentration was 0-2.5 mmol/L.
Peritoneal lactate concentrations in healthy post-partum mares remained within the normal reference range and were not influenced by RFM or parturition. Increased peritoneal lactate in this group warrants further investigation.
To compare blood and peritoneal lactate concentrations in a population of mares within 36 h post-partum, report a normal reference range and identify any impact of retained foetal membranes (RFMs).
This is a retrospective study evaluating healthy mares from which blood and peritoneal samples had been obtained within 36 h of parturition. Exclusion criteria included signs of abdominal pain within this period. Data was interrogated for normality using a Shapiro-Wilk test. Wilcoxon signed-rank test and Bland-Altman analysis were used to compare blood and peritoneal lactate concentrations. Linear regression was used to compare age and breed data with peritoneal lactate concentrations. Significance was defined as p < 0.05.
Forty mares met the inclusion criteria. Mean age was 12.6 ± 4.1 years, and most mares were multiparous (65%). Peritoneal lactate ((1.2 (IQR = 0.9-1.6) mmol/L) was increased compared to blood lactate concentration (0.7 (IQR = 0-1.1)mmol/L; p < 0.001). Plasma total protein (TP) concentrations were 68 (IQR = 64-74) g/L and peritoneal protein concentrations 8 (IQR = 4-9.7) g/L. Six mares developed RFM. The median fold-increase in peritoneal lactate concentration compared to blood lactate concentration was 0.9 (IQR: 0.01-1.7; range: 0-2.5). The reference range for peritoneal fluid lactate concentration was 0-2.5 mmol/L.
Peritoneal lactate concentrations in healthy post-partum mares remained within the normal reference range and were not influenced by RFM or parturition. Increased peritoneal lactate in this group warrants further investigation.
摘要：
背景：腹膜液乳酸浓度是马腹痛的重要诊断工具。母马分娩后缺乏有关腹膜乳酸浓度的信息。
目的：比较母马在产后36小时内的血液和腹膜乳酸浓度，报告正常参考范围，并确定保留的胎膜（RFM）的任何影响。
方法：这是一项回顾性研究，评估在分娩后36小时内获得血液和腹膜样本的健康母马。排除标准包括在此期间的腹痛体征。使用Shapiro-Wilk检验询问数据的正常性。使用Wilcoxon符号秩检验和Bland-Altman分析比较血液和腹膜乳酸浓度。线性回归用于比较年龄和品种数据与腹膜乳酸浓度。显著性定义为p<0.05。
结果：40匹母马符合纳入标准。平均年龄为12.6±4.1岁，大多数母马是经产的(65%)。与血乳酸浓度（0.7（IQR=0-1.1）mmol/L；p<0.001）相比，腹膜乳酸（（1.2（IQR=0.9-1.6）mmol/L）增加。血浆总蛋白（TP）浓度为68（IQR=64-74）g/L，腹膜蛋白浓度为8（IQR=4-9.7）g/L。六匹母马开发了RFM。与血乳酸浓度相比，腹膜乳酸浓度的中位倍数增加为0.9（IQR：0.01-1.7；范围：0-2.5）。腹腔液乳酸浓度的参考范围为0-2.5mmol/L。
结论：健康产后母马的腹膜乳酸浓度保持在正常参考范围内，不受RFM或分娩的影响。该组中腹膜乳酸的增加值得进一步研究。
目的：比较母马在产后36小时内的血液和腹膜乳酸浓度，报告正常参考范围，并确定保留的胎膜（RFM）的任何影响。
方法：这是一项回顾性研究，评估在分娩后36小时内获得血液和腹膜样本的健康母马。排除标准包括在此期间的腹痛体征。使用Shapiro-Wilk检验询问数据的正常性。使用Wilcoxon符号秩检验和Bland-Altman分析比较血液和腹膜乳酸浓度。线性回归用于比较年龄和品种数据与腹膜乳酸浓度。显著性定义为p<0.05。
结果：40匹母马符合纳入标准。平均年龄为12.6±4.1岁，大多数母马是经产的(65%)。与血乳酸浓度（0.7（IQR=0-1.1）mmol/L；p<0.001）相比，腹膜乳酸（（1.2（IQR=0.9-1.6）mmol/L）增加。血浆总蛋白（TP）浓度为68（IQR=64-74）g/L，腹膜蛋白浓度为8（IQR=4-9.7）g/L。六匹母马开发了RFM。与血乳酸浓度相比，腹膜乳酸浓度的中位倍数增加为0.9（IQR：0.01-1.7；范围：0-2.5）。腹腔液乳酸浓度的参考范围为0-2.5mmol/L。
结论：健康产后母马的腹膜乳酸浓度保持在正常参考范围内，不受RFM或分娩的影响。该组中腹膜乳酸的增加值得进一步研究。
