PDF(Pubmed)
Abstract：
The diagnosis of Lyme disease is becoming more common in Turkey. Nonetheless, some physicians are not aware of the diagnostic principles that should be followed when faced with a suspected patient and could use tests that are not recommended, such as darkfield microscopy. Dark field microscopy is a diagnostic technique to visualize the spirochetes that cause Lyme disease; however, it is not recommended for the diagnosis of Lyme disease. One of the main limitations of dark field microscopy is its low sensitivity. Another limitation is its high false-positivity rate, as other microorganisms and cellular debris can be mistaken for spirochetes, leading to a misdiagnosis thatmay result in unnecessary treatment. Therefore, this study aimed to review the literature on the role of dark field microscopy as a diagnostic method for Lyme disease and inform physicians about recommended approaches in line with the recommendations of national or international guidelines. An electronic search of Pubmed, Scopus, and Web of Science was performed using the following medical subject headings (MeSH) search terms: Lyme borreliosis, Lyme disease, Borrelia burgdorferi, diagnosis, and microscopy. With this narrative review, we aimed to inform physicians better and improve patient care for patients with suspected Lyme disease.
摘要：
莱姆病的诊断在土耳其越来越普遍。尽管如此，一些医生不知道面对可疑患者时应该遵循的诊断原则，可以使用不推荐的测试，如暗场显微镜。暗视野显微镜是一种诊断技术，用于可视化导致莱姆病的螺旋体；然而，不建议诊断莱姆病。暗视野显微镜的主要限制之一是其灵敏度低。另一个限制是它的高假阳性率，因为其他微生物和细胞碎片可能被误认为螺旋体，导致误诊，可能导致不必要的治疗。因此,本研究旨在回顾有关暗视野显微镜作为莱姆病诊断方法的作用的文献,并向医师介绍符合国家或国际指南建议的推荐方法.电子搜索Pubmed，Scopus,和WebofScience使用以下医学主题词(MeSH)搜索术语进行：莱姆病，莱姆病,伯氏疏螺旋体,诊断,和显微镜。通过这篇叙述性评论，我们旨在更好地告知医生,并改善疑似莱姆病患者的患者护理.
