关键词: Interferonopathy SAVI STING Uveitis Vasculitis

来  源:   DOI:10.1016/j.ajoc.2024.102046   PDF(Pubmed)

Abstract:
UNASSIGNED: To describe a case of bilateral panuveitis in a patient with Stimulator of Interferon Genes (STING)-Associated Vasculitis with Onset in Infancy (SAVI).
UNASSIGNED: A 45-year-old patient diagnosed with SAVI presented bilateral panuveitis and uncontrolled secondary intraocular hypertension due to structural complications from uveitis. Multimodal imaging revealed the presence of intraretinal fluid and bilateral vasculitis. The patient was started with systemic methotrexate.
UNASSIGNED: This case is essential to characterize ocular involvement in patients with SAVI. Awareness of these ocular manifestations is crucial for timely management and improvement of visual prognosis.
摘要:
描述一例患有干扰素基因刺激因子(STING)相关血管炎并在婴儿期(SAVI)发作的患者的双侧全葡萄膜炎。
一名诊断为SAVI的45岁患者由于葡萄膜炎的结构性并发症而出现双侧全葡萄膜炎和不受控制的继发性高眼压。多模态成像显示存在视网膜内液和双侧血管炎。患者开始使用全身性甲氨蝶呤。
这种情况对于表征SAVI患者的眼部受累至关重要。意识到这些眼部表现对于及时治疗和改善视觉预后至关重要。
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