Abstract：
BACKGROUND: The use of hemostatic agents by general surgeons during abdominal operations is commonplace as an adjunctive measure to minimize risks of postoperative bleeding and its downstream complications. Proper selection of products can be hampered by marginal understanding of their pharmacokinetics and pharmacodynamics. While a variety of hemostatic agents are currently available on the market, the choice of those products is often confusing for surgeons. This paper aims to summarize and compare the available hemostatic products for each clinical indication and to ultimately better guide surgeons in the selection and proper use of hemostatic agents in daily clinical practice.
METHODS: We utilized PubMed electronic database and published product information from the respective pharmaceutical companies to collect information on the characteristics of the hemostatic products.
RESULTS: All commercially available hemostatic agents in the US are described with a description of their mechanism of action, indications, contraindications, circumstances in which they are best utilized, and expected results.
CONCLUSIONS: Hemostatic products come with many different types and specifications. They are valuable tools to serve as an adjunct to surgical hemostasis. Proper education and knowledge of their characteristics are important for the selection of the right agent and optimal utilization.
METHODS: We utilized PubMed electronic database and published product information from the respective pharmaceutical companies to collect information on the characteristics of the hemostatic products.
RESULTS: All commercially available hemostatic agents in the US are described with a description of their mechanism of action, indications, contraindications, circumstances in which they are best utilized, and expected results.
CONCLUSIONS: Hemostatic products come with many different types and specifications. They are valuable tools to serve as an adjunct to surgical hemostasis. Proper education and knowledge of their characteristics are important for the selection of the right agent and optimal utilization.
摘要：
背景：普通外科医师在腹部手术期间使用止血剂是一种常见的辅助措施，以最大程度地减少术后出血及其下游并发症的风险。对产品的正确选择可能会受到对其药代动力学和药效学的边际理解的阻碍。虽然目前市场上有多种止血剂，这些产品的选择通常会让外科医生感到困惑。本文旨在总结和比较每种临床适应症可用的止血产品，最终更好地指导外科医生在日常临床实践中选择和正确使用止血剂。
方法：我们利用PubMed电子数据库和各自制药公司发布的产品信息来收集有关止血产品特性的信息。
结果：美国所有市售的止血剂均描述了其作用机理，适应症,禁忌症,它们得到最好利用的情况，和预期的结果。
结论：止血产品有许多不同的类型和规格。它们是作为手术止血的辅助手段的有价值的工具。正确的教育和对其特征的了解对于选择正确的代理和最佳利用至关重要。
方法：我们利用PubMed电子数据库和各自制药公司发布的产品信息来收集有关止血产品特性的信息。
结果：美国所有市售的止血剂均描述了其作用机理，适应症,禁忌症,它们得到最好利用的情况，和预期的结果。
结论：止血产品有许多不同的类型和规格。它们是作为手术止血的辅助手段的有价值的工具。正确的教育和对其特征的了解对于选择正确的代理和最佳利用至关重要。
