PDF(Pubmed)
Abstract：
The aim of the present study was to investigate the possibility of reducing the damage to the donor site while preserving the functional recovery of the dorsum of the hand following burn injury. An attempt was made to analyze the effect of a phased surgery approach on inflammatory indicators. A two-phase treatment was administered on a total of 64 patients with deep second-degree burns on the dorsum of the hand who were admitted to Guangzhou Red Cross Hospital between January 2020 and March 2023. During phase I treatment, the wounds were covered with xenogeneic (porcine) skin, followed by the application of autologous thin intermediate thickness skin grafts for wound repair in phase II treatment 1 week later. The surgical results, complications, patient satisfaction and inflammatory response indicators were then analyzed. The mean wound healing time of these patients was found to be 21.94 days without complications. The mean survival rate was 98.66%, and the overall satisfaction score of the patients was high. Finally, the white blood cell, C-reactive protein and IL-6 levels of these patients were continuously decreased 2 days preoperatively and 2 days postoperatively in phase I, and 2 days preoperatively and 2 days postoperatively in phase II. In combination, the effect of phased autologous skin grafting in patients with severe second-degree burns on the dorsum of the hand was ideal, as it significantly reduced inflammatory response and was beneficial to the functional recovery of the hand. Therefore, phased autologous skin grafting is worthy of wider application.
摘要：
本研究的目的是研究在烧伤后保留手背功能恢复的同时减少供体部位损伤的可能性。尝试分析分阶段手术方法对炎症指标的影响。对2020年1月至2023年3月期间入住广州市红十字会医院的64例手部背部深二度烧伤患者进行了两阶段治疗。在第一阶段治疗期间，伤口被异种（猪）皮肤覆盖，然后在1周后的II期治疗中应用自体薄的中间厚度皮肤移植物进行伤口修复。手术结果,并发症,然后分析患者满意度和炎症反应指标。这些患者的平均伤口愈合时间为21.94天，无并发症。平均生存率为98.66%,患者的总体满意度得分较高。最后,白细胞,这些患者术前2天和术后2天C反应蛋白和IL-6水平在I期持续下降,以及术前2天和术后2天的II期。在组合中，重度Ⅱ度烧伤患者手背分期自体皮移植效果理想,因为它显著降低炎症反应，有利于手的功能恢复。因此,分期自体皮肤移植值得更广泛的应用。
