关键词: Cardiovascular medicine Haematology (incl blood transfusion) Valvar diseases

Mesh : Male Humans ST Elevation Myocardial Infarction / etiology Aortic Valve / diagnostic imaging Hypereosinophilic Syndrome / complications diagnosis drug therapy Hydroxyurea Thrombosis / diagnostic imaging drug therapy etiology

来  源:   DOI:10.1136/bcr-2023-259494   PDF(Pubmed)

Abstract:
We present a case of a man in his 30s presenting with ST-segment elevation myocardial infarction and eosinophilia. The patient underwent thrombus aspiration and initially echocardiographic evaluation was normal. The patient was discharged after 2 days, but was hospitalised again after 6 days. Echocardiographic evaluation now revealed a thrombus formation on the aortic valve. Laboratory data revealed increasing eosinophilia, and treatment with high-dosage corticosteroids and hydroxyurea was initiated as eosinophilic disease with organ manifestations could not be precluded. Eosinophils normalised and the patient was discharged again. The combination of hypereosinophilia and absence of infection, rheumatological disorders and malignancy, led to reactive or idiopathic hypereosinophilic syndrome being the most plausible diagnoses. The patient was closely monitored in the cardiology and haematology outpatient clinics. Echocardiographic evaluation, performed 6 weeks after the patient was discharged, showed significant regression in the size of the thrombus mass.
摘要:
我们介绍了一例30多岁的男子,表现为ST段抬高型心肌梗死和嗜酸性粒细胞增多。患者接受了血栓抽吸术,最初的超声心动图评估正常。患者2天后出院,但6天后再次住院。超声心动图评估现在显示主动脉瓣上有血栓形成。实验室数据显示嗜酸性粒细胞增多,由于不能排除有器官表现的嗜酸性粒细胞疾病,因此开始接受高剂量糖皮质激素和羟基脲治疗.嗜酸性粒细胞恢复正常,患者再次出院。嗜酸性粒细胞增多和没有感染的组合,风湿性疾病和恶性肿瘤,导致反应性或特发性嗜酸性粒细胞增多综合征是最合理的诊断。在心脏病学和血液学门诊密切监测患者。超声心动图评价,在患者出院后6周进行,显示血栓块大小的显着回归。
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