PDF(Pubmed)
Abstract：
OBJECTIVE: Cerebral venous thrombosis (CVT) is a rare cerebrovascular disorder that mainly affects young and middle-aged adults. Epidemiological data on the incidence, risk factors, diagnosis, treatment, and prognosis of CVT are lacking in China. In addition, there is a lack of evidence from large, multicenter, real-world studies on the efficacy and safety of endovascular.
OBJECTIVE: To understand the incidence, diagnosis and treatment status of CVT in China and to estimate the effectiveness and safety of endovascular treatment in the real-world.
METHODS: A multicenter, retrospective observational cohort study will be conducted on CVT patient records from 104 hospitals, between January 1, 2018 and June 30, 2022, identified using a 2-stage cluster sampling design based on per capita gross domestic product. Each enrolled participant is required to complete a further follow-up, which includes the current situation and the assessment at 3 and 12 months after discharge.
RESULTS: The outcomes of this study will include the current status of the incidence, pathogenesis, etiology, clinical symptoms, diagnosis, and treatment of CVT in China, as well as the effectiveness and safety of endovascular treatment in the real-world.
CONCLUSIONS: Results from this study will provide evidence on the incidence, specific risk factors, symptomatic and imaging features, and clinical outcomes of CVT in China as well as indicate whether endovascular treatment is superior to medical management alone for patients with acute CVT in the real-world.
BACKGROUND: http://www.
RESULTS: gov.
UNASSIGNED: NCT05448248.
OBJECTIVE: To understand the incidence, diagnosis and treatment status of CVT in China and to estimate the effectiveness and safety of endovascular treatment in the real-world.
METHODS: A multicenter, retrospective observational cohort study will be conducted on CVT patient records from 104 hospitals, between January 1, 2018 and June 30, 2022, identified using a 2-stage cluster sampling design based on per capita gross domestic product. Each enrolled participant is required to complete a further follow-up, which includes the current situation and the assessment at 3 and 12 months after discharge.
RESULTS: The outcomes of this study will include the current status of the incidence, pathogenesis, etiology, clinical symptoms, diagnosis, and treatment of CVT in China, as well as the effectiveness and safety of endovascular treatment in the real-world.
CONCLUSIONS: Results from this study will provide evidence on the incidence, specific risk factors, symptomatic and imaging features, and clinical outcomes of CVT in China as well as indicate whether endovascular treatment is superior to medical management alone for patients with acute CVT in the real-world.
BACKGROUND: http://www.
RESULTS: gov.
UNASSIGNED: NCT05448248.
摘要：
目的：脑静脉血栓形成（CVT）是一种罕见的脑血管疾病，主要影响中青年成年人。关于发病率的流行病学数据，危险因素，诊断,治疗,中国缺乏CVT的预后。此外,缺乏大量证据，多中心，关于血管内治疗的有效性和安全性的真实世界研究。
目的：了解发病率，中国CVT的诊断和治疗现状，并评估真实世界中血管内治疗的有效性和安全性。
方法：多中心，回顾性观察性队列研究将对来自104家医院的CVT患者记录进行，在2018年1月1日至2022年6月30日之间，使用基于人均国内生产总值的2阶段整群抽样设计确定。每个注册的参与者都需要完成进一步的随访，其中包括目前的情况以及出院后3个月和12个月的评估。
结果：这项研究的结果将包括发病率的现状，发病机制，病因学,临床症状,诊断,以及中国CVT的治疗，以及血管内治疗在现实世界中的有效性和安全性。
结论：这项研究的结果将为发病率提供证据，特定的风险因素，症状和影像学特征，和中国CVT的临床结果，以及在现实世界中，对于急性CVT患者，血管内治疗是否优于单独的医疗管理。
背景：http://www.
结果：政府。
■NCT05448248。
目的：了解发病率，中国CVT的诊断和治疗现状，并评估真实世界中血管内治疗的有效性和安全性。
方法：多中心，回顾性观察性队列研究将对来自104家医院的CVT患者记录进行，在2018年1月1日至2022年6月30日之间，使用基于人均国内生产总值的2阶段整群抽样设计确定。每个注册的参与者都需要完成进一步的随访，其中包括目前的情况以及出院后3个月和12个月的评估。
结果：这项研究的结果将包括发病率的现状，发病机制，病因学,临床症状,诊断,以及中国CVT的治疗，以及血管内治疗在现实世界中的有效性和安全性。
结论：这项研究的结果将为发病率提供证据，特定的风险因素，症状和影像学特征，和中国CVT的临床结果，以及在现实世界中，对于急性CVT患者，血管内治疗是否优于单独的医疗管理。
背景：http://www.
结果：政府。
■NCT05448248。
