Abstract：
This study assesses the impact of an advanced intermittent pneumatic compression device (IPC - Lympha Press® Optimal Plus) when added to Complete Decongestive Therapy (CDT) compared to CDT alone on volume reduction of limbs with lymphedema. The goal is to maximally reduce edema in preparation for microsurgery. Fifty subjects scheduled for Multiple Lymphatic-Venous Anastomosis (MLVA) were randomly (sequentially) assigned to experimental or control group: 25 (21 females and 4 males) in the experimental IPC group and 25 (20 females and 5 males) in the control group. The two groups were similar in age, sex distribution, and type of lymphedema. Results indicate the IPC group reported greater volume loss than the control group (p= 0.00137) comparing final vs. initial limb volume. The average percentage edema volume loss achieved with added IPC was two times greater (11.7%) than in the control group (5.0%). When differences in treatment duration were accounted for, the IPC group achieved consistently greater proportional volume loss (12.83% vs 6.30%) than conservative therapy alone. In our pilot study, IPC added to CDT resulted in greater proportional volume loss and provides better preparation for MLVA surgery.
摘要：
这项研究评估了与完全充血疗法（CDT）相比，与单独的CDT相比，高级间歇性气动压缩装置（IPC-LymphaPress®OptimalPlus）对淋巴水肿四肢体积减少的影响。目标是在准备显微外科手术时最大程度地减少水肿。计划进行多次淋巴静脉吻合术（MLVA）的50名受试者被随机（顺序）分配到实验组或对照组：实验IPC组25名（21名女性和4名男性），对照组25名（20名女性和5名男性）。两组年龄相似,性别分布，淋巴水肿的类型.结果表明，IPC组报告的体积损失大于对照组（p=0.00137），比较最终与初始肢体体积。添加IPC的平均水肿体积损失百分比（11.7％）是对照组（5.0％）的两倍。当考虑到治疗持续时间的差异时，与单独的保守治疗相比,IPC组实现了持续更大的比例体积损失(12.83%vs6.30%).在我们的试点研究中，添加到CDT的IPC导致更大的比例体积损失，并为MLVA手术提供更好的准备。
