Abstract：
BACKGROUND: Tooth brushing is a universal recommendation. However, the recommendations related to the time of its execution are conflicting, especially when dealing with patients at risk of erosive tooth wear (ETW) or dental caries.
CONCLUSIONS: Our objective was to summarize the evidence on the timing of brushing with fluoridated toothpaste in relation to ETW and cariogenic dietary challenges. We conducted a scoping review following the PRISMA-ScR checklist, using three databases searching for in vivo, in situ, or in vitro studies involving human teeth exposed to either a cariogenic or an erosive challenge. Only models including human saliva and fluoride were assessed. Data selection, extraction, and risk of bias analysis were done in duplicate and independently. From 1,545 identified studies, 17 (16 related to ETW and 1 to dental caries) were included. Most evidence (n = 10) supported that brushing with a fluoride-containing product does not increase ETW, independent of the moment of brushing. Delaying tooth brushing up to 1 h (n = 4) or individualized recommendations based on the patient\'s problem (n = 2) were less frequent. Only one study reported that brushing pre- or post-meal does not affect Streptococcus mutans counts. Most data were in situ (n = 13), and the overall study quality was judged as sufficient/low risk of bias.
CONCLUSIONS: Although the available evidence lacked robust clinical studies, tooth brushing using fluoridated products immediately after an erosive challenge does not increase the risk of ETW and can be recommended, which is in line with recommendations for dental caries prevention. Furthermore, we suggest updating the international guidelines to promote individualized recommendations based on risk factors to prevent either ETW or dental caries.
CONCLUSIONS: Our objective was to summarize the evidence on the timing of brushing with fluoridated toothpaste in relation to ETW and cariogenic dietary challenges. We conducted a scoping review following the PRISMA-ScR checklist, using three databases searching for in vivo, in situ, or in vitro studies involving human teeth exposed to either a cariogenic or an erosive challenge. Only models including human saliva and fluoride were assessed. Data selection, extraction, and risk of bias analysis were done in duplicate and independently. From 1,545 identified studies, 17 (16 related to ETW and 1 to dental caries) were included. Most evidence (n = 10) supported that brushing with a fluoride-containing product does not increase ETW, independent of the moment of brushing. Delaying tooth brushing up to 1 h (n = 4) or individualized recommendations based on the patient\'s problem (n = 2) were less frequent. Only one study reported that brushing pre- or post-meal does not affect Streptococcus mutans counts. Most data were in situ (n = 13), and the overall study quality was judged as sufficient/low risk of bias.
CONCLUSIONS: Although the available evidence lacked robust clinical studies, tooth brushing using fluoridated products immediately after an erosive challenge does not increase the risk of ETW and can be recommended, which is in line with recommendations for dental caries prevention. Furthermore, we suggest updating the international guidelines to promote individualized recommendations based on risk factors to prevent either ETW or dental caries.
摘要：
背景：刷牙是一种普遍的建议。然而,与执行时间相关的建议是相互矛盾的，特别是在处理有糜烂牙齿磨损（ETW）或龋齿风险的患者时。
结论：我们的目的是总结与ETW和致龋饮食挑战有关的氟化牙膏刷牙时间的证据。我们根据PRISMA-ScR清单进行了范围审查，使用三个数据库搜索体内，就地,或涉及人类牙齿暴露于龋齿或侵蚀性挑战的体外研究。仅评估包括人唾液和氟化物的模型。数据选择,提取,和偏倚风险分析是重复和独立进行的。从1545项确定的研究中，包括17个（16个与ETW有关，1个与龋齿有关）。大多数证据（n=10）支持用含氟产品刷牙不会增加ETW，独立于刷牙的时刻。延迟刷牙1小时（n=4）或基于患者问题的个性化建议（n=2）频率较低。只有一项研究报告说，餐前或餐后刷牙不会影响变形链球菌的计数。大多数数据是原位数据(n=13)，总体研究质量被判定为足够/低偏倚风险.
结论：尽管现有证据缺乏有力的临床研究，在侵蚀性挑战后立即使用氟化产品刷牙不会增加ETW的风险，可以推荐，这符合龋齿预防的建议。此外，我们建议更新国际指南,根据危险因素提出个性化建议,以预防ETW或龋齿.
结论：我们的目的是总结与ETW和致龋饮食挑战有关的氟化牙膏刷牙时间的证据。我们根据PRISMA-ScR清单进行了范围审查，使用三个数据库搜索体内，就地,或涉及人类牙齿暴露于龋齿或侵蚀性挑战的体外研究。仅评估包括人唾液和氟化物的模型。数据选择,提取,和偏倚风险分析是重复和独立进行的。从1545项确定的研究中，包括17个（16个与ETW有关，1个与龋齿有关）。大多数证据（n=10）支持用含氟产品刷牙不会增加ETW，独立于刷牙的时刻。延迟刷牙1小时（n=4）或基于患者问题的个性化建议（n=2）频率较低。只有一项研究报告说，餐前或餐后刷牙不会影响变形链球菌的计数。大多数数据是原位数据(n=13)，总体研究质量被判定为足够/低偏倚风险.
结论：尽管现有证据缺乏有力的临床研究，在侵蚀性挑战后立即使用氟化产品刷牙不会增加ETW的风险，可以推荐，这符合龋齿预防的建议。此外，我们建议更新国际指南,根据危险因素提出个性化建议,以预防ETW或龋齿.
