PDF(Pubmed)
Abstract：
Multisystem inflammatory syndrome in adults (MIS-A) is a systemic inflammatory disease associated with COVID-19 and follows coronary artery aneurysms similar to Kawasaki disease. In many cases, it is improved by treatments such as high-dose steroids or intravenous immunoglobulin (IVIg). However, the role of untreated coronary artery aneurysms leading to future stenosis remains unknown. Untreated MIS-A may potentially lead to the formation of coronary aneurysms. In cases of COVID-19 where young adults present with angina-like symptoms, an evaluation for angina is considered. Herein, we report a case of a 27-year-old female who developed unstable angina with coronary artery aneurysms six months after COVID-19 infection. She required surgery for unstable angina, which resulted in an improvement in chest pain. Coronary artery lesions are considered to be related to MIS-A, and treatment was conducted in accordance with that for Kawasaki disease. Currently, the pathological differences and prognosis between MIS-A and Kawasaki disease remain unclear, but the elucidation of the conditions is warranted in the future.
摘要：
成人多系统炎症综合征（MIS-A）是一种与COVID-19相关的全身性炎症性疾病，与川崎病相似。在许多情况下,通过大剂量类固醇或静脉注射免疫球蛋白（IVIg）等治疗来改善。然而,未经治疗的冠状动脉瘤导致未来狭窄的作用尚不清楚.未经治疗的MIS-A可能潜在地导致冠状动脉瘤的形成。在COVID-19的病例中，年轻人出现心绞痛样症状，考虑对心绞痛的评估。在这里，我们报告了一例27岁女性病例,她在COVID-19感染6个月后出现不稳定型心绞痛伴冠状动脉瘤.她因不稳定型心绞痛需要手术,导致胸痛的改善。冠状动脉病变被认为与MIS-A有关，并按照川崎病进行治疗。目前,MIS-A与川崎病的病理学差异和预后尚不清楚，但是将来有必要阐明条件。
