PDF(Pubmed)
Abstract：
BACKGROUND: Focal nodular hyperplasia is a common nonmalignant liver mass. This nonvascular lesion is an uncommon mass in children, especially those with no predisposing factors, namely radiation, chemotherapy, and hematopoietic stem cell therapy. Exophytic growth of the lesion further than the liver margins is not common and can complicate the diagnosis of the lesion. This report observes a focal nodular hyperplasia as a pedunculated lesion in a healthy child.
METHODS: We describe a 9-year-old healthy Persian child who was born following in vitro fertilization complaining of abdominal pain lasting for months and palpitation. Employing ultrasound and computed tomography, a mass was detected in the right upper quadrant compatible with focal nodular hyperplasia imaging features. The child underwent surgery and the mass was resected.
CONCLUSIONS: Diagnosing focal nodular hyperplasia, especially pedunculated form can be challenging, although magnetic resonance imaging with scintigraphy is nearly 100% sensitive and specific. Thus, a biopsy may be needed to rule out malignancies in some cases. Deterministic treatment in patients with suspicious mass, remarkable growth of lesion in serial examination, and persistent symptoms, such as pain, is resection, which can be done open or laparoscopic.
METHODS: We describe a 9-year-old healthy Persian child who was born following in vitro fertilization complaining of abdominal pain lasting for months and palpitation. Employing ultrasound and computed tomography, a mass was detected in the right upper quadrant compatible with focal nodular hyperplasia imaging features. The child underwent surgery and the mass was resected.
CONCLUSIONS: Diagnosing focal nodular hyperplasia, especially pedunculated form can be challenging, although magnetic resonance imaging with scintigraphy is nearly 100% sensitive and specific. Thus, a biopsy may be needed to rule out malignancies in some cases. Deterministic treatment in patients with suspicious mass, remarkable growth of lesion in serial examination, and persistent symptoms, such as pain, is resection, which can be done open or laparoscopic.
摘要：
背景：局灶性结节增生是一种常见的非恶性肝脏肿块。这种非血管病变在儿童中并不常见，尤其是那些没有诱发因素的人，即辐射，化疗,和造血干细胞治疗.病变的外生性生长超过肝脏边缘并不常见，并且可能使病变的诊断复杂化。本报告观察到健康儿童的局灶性结节增生是带蒂病变。
方法：我们描述了一个9岁健康的波斯儿童，他在体外受精后出生，抱怨腹痛持续数月和心悸。采用超声波和计算机断层扫描，在右上象限检测到与局灶性结节增生成像特征相符的肿块.孩子接受了手术，肿块被切除。
结论：诊断局灶性结节增生，尤其是有花梗的形式可能具有挑战性，尽管闪烁扫描的磁共振成像几乎100％敏感和特异性。因此，在某些情况下，可能需要进行活检以排除恶性肿瘤。可疑肿块患者的确定性治疗，连续检查中病变的显着增长，和持续的症状，如疼痛，是切除，可以开腹或腹腔镜。
方法：我们描述了一个9岁健康的波斯儿童，他在体外受精后出生，抱怨腹痛持续数月和心悸。采用超声波和计算机断层扫描，在右上象限检测到与局灶性结节增生成像特征相符的肿块.孩子接受了手术，肿块被切除。
结论：诊断局灶性结节增生，尤其是有花梗的形式可能具有挑战性，尽管闪烁扫描的磁共振成像几乎100％敏感和特异性。因此，在某些情况下，可能需要进行活检以排除恶性肿瘤。可疑肿块患者的确定性治疗，连续检查中病变的显着增长，和持续的症状，如疼痛，是切除，可以开腹或腹腔镜。
