Abstract：
OBJECTIVE: The purpose of this manuscript was twofold: to investigate how clinical voice and swallow questionnaires align with self-reports from speech/voice and swallow domains of the Unified Parkinson\'s Disease Rating Scale (UPDRS), and how decline in self-reported speech/voice measures predict decline in self-reported swallowing measures.
METHODS: This observational, preliminary cross-sectional study included 15 people diagnosed with Idiopathic Parkinson\'s Disease. Participants completed the Voice Related Quality of Life (V-RQOL), Sydney Swallow Questionnaire (SSQ), and cognitive screening (Montreal Cognitive Assessment; MoCA) to account for cognitive impairment during self-reported speech/voice and swallow measures. They also completed the speech/voice and swallow components of the UPDRS.
RESULTS: There were significant associations between the SSQ and UPDRS question 2.3 (chewing/swallowing) (P < 0.001), but not between UPDRS question 2.1 (speech/voice) and V-RQOL. However, the MoCA was significantly and directionally associated with V-RQOL scores (P = 0.01). Finally, the V-RQOL was significantly associated with SSQ scores in a multiple regression model (P = 0.02).
CONCLUSIONS: Speech/voice and swallow-related questions from the UPDRS may be viable initial screening tools to facilitate faster and earlier laryngeal function testing. Substantially more research should be undertaken to assess how well these UPDRS question domains are indicative of underlying speech/voice or swallow dysfunction.
METHODS: This observational, preliminary cross-sectional study included 15 people diagnosed with Idiopathic Parkinson\'s Disease. Participants completed the Voice Related Quality of Life (V-RQOL), Sydney Swallow Questionnaire (SSQ), and cognitive screening (Montreal Cognitive Assessment; MoCA) to account for cognitive impairment during self-reported speech/voice and swallow measures. They also completed the speech/voice and swallow components of the UPDRS.
RESULTS: There were significant associations between the SSQ and UPDRS question 2.3 (chewing/swallowing) (P < 0.001), but not between UPDRS question 2.1 (speech/voice) and V-RQOL. However, the MoCA was significantly and directionally associated with V-RQOL scores (P = 0.01). Finally, the V-RQOL was significantly associated with SSQ scores in a multiple regression model (P = 0.02).
CONCLUSIONS: Speech/voice and swallow-related questions from the UPDRS may be viable initial screening tools to facilitate faster and earlier laryngeal function testing. Substantially more research should be undertaken to assess how well these UPDRS question domains are indicative of underlying speech/voice or swallow dysfunction.
摘要：
目的：本手稿的目的是双重的：调查临床语音和吞咽问卷如何与统一帕金森病评定量表（UPDRS）的语音/语音和吞咽领域的自我报告保持一致，以及自我报告的语音/语音指标的下降如何预测自我报告的吞咽指标的下降。
方法：这种观察，初步横断面研究包括15名诊断为特发性帕金森病的患者。参与者完成了语音相关生活质量（V-RQOL），悉尼燕子问卷(SSQ)，和认知筛查（蒙特利尔认知评估；MoCA），以解释自我报告的言语/语音和吞咽措施期间的认知障碍。他们还完成了UPDRS的语音/语音和吞咽组件。
结果：SSQ和UPDRS问题2.3（咀嚼/吞咽）之间存在显着关联（P<0.001），但不在UPDRS问题2.1（语音/语音）和V-RQOL之间。然而,MoCA与V-RQOL评分显著相关(P=0.01)。最后,在多元回归模型中,V-RQOL与SSQ评分显著相关(P=0.02).
结论：来自UPDRS的语音/语音和吞咽相关问题可能是可行的初始筛查工具，以促进更快，更早的喉功能测试。应进行更多的研究以评估这些UPDRS问题域指示潜在的语音/语音或吞咽功能障碍的程度。
方法：这种观察，初步横断面研究包括15名诊断为特发性帕金森病的患者。参与者完成了语音相关生活质量（V-RQOL），悉尼燕子问卷(SSQ)，和认知筛查（蒙特利尔认知评估；MoCA），以解释自我报告的言语/语音和吞咽措施期间的认知障碍。他们还完成了UPDRS的语音/语音和吞咽组件。
结果：SSQ和UPDRS问题2.3（咀嚼/吞咽）之间存在显着关联（P<0.001），但不在UPDRS问题2.1（语音/语音）和V-RQOL之间。然而,MoCA与V-RQOL评分显著相关(P=0.01)。最后,在多元回归模型中,V-RQOL与SSQ评分显著相关(P=0.02).
结论：来自UPDRS的语音/语音和吞咽相关问题可能是可行的初始筛查工具，以促进更快，更早的喉功能测试。应进行更多的研究以评估这些UPDRS问题域指示潜在的语音/语音或吞咽功能障碍的程度。
