Abstract:
Pituitary incidentalomas are common findings with increasing use of modern neuroradiological imaging undertaken for symptoms unrelated to pituitary disease. The prevalence of these lesions is ∼10% in autopsy studies and the incidence varies from 10% to 38% on magnetic resonance imaging in the published literature. They are almost always benign in nature and most are non-functioning (non-secreting) adenomas. Although many individuals are asymptomatic at diagnosis, some with functioning (secreting) pituitary adenomas or larger non-functioning adenomas have symptoms. All identified cases should have a thorough clinical and endocrinological evaluation to help with precise management, which depends on the size of the lesion, hormonal status (functioning versus non-functioning adenoma) and the presence of visual deficits resulting from optic nerve compression by the pituitary adenoma. Here, we provide an overview of the initial assessment and management of pituitary incidentalomas for clinicians not routinely involved in the management of pituitary disease.
摘要:
垂体偶发瘤是与垂体疾病无关的症状越来越多地使用现代神经放射学影像学检查的常见发现。在尸检研究中,这些病变的患病率约为10%,在已发表的文献中,磁共振成像的发病率从10%到38%不等。它们本质上几乎总是良性的,大多数是无功能(非分泌性)腺瘤。尽管许多人在诊断时无症状,一些功能性(分泌性)垂体腺瘤或较大的无功能腺瘤有症状。所有确定的病例都应进行全面的临床和内分泌评估,以帮助进行精确的管理,这取决于病变的大小,激素状态(功能性腺瘤与非功能性腺瘤)以及垂体腺瘤对视神经的压迫导致的视觉缺陷。这里,我们为未常规参与垂体疾病治疗的临床医师提供垂体偶发瘤的初步评估和治疗的概述.