PDF(Pubmed)
Abstract：
Presently, there has been an increase in the consumption of the blue-green microalga-spirulina (Arthrospira species), which dominates 99.5% of the total world production of microalgae. Primarily sold as a dietary supplement, it is also incorporated into snacks, pasta, cookies, and bread. Owing to its nutrient abundance, spirulina has a variety of potential applications. Extensive studies have been conducted on the health benefits of spirulina, but its safety in terms of allergy has received limited attention. Therefore, to bridge this knowledge deficit, this review aimed to evaluate the allergenic and antiallergic potential of spirulina. In the PubMed and Scopus databases using words related to allergy, we attempted to detect papers on hypersensitivity to spirulina. A total of 128 records were identified, of which 49 were screened. Ultimately, in this review, we analyzed four case studies, encompassing a total of five patients with allergies to spirulina. We assessed the severity of allergic reactions following World Allergy Organization (WAO) Anaphylaxis Guidance 2020, which varied from mild (grade 2) to severe (grade 4) based on the patient\'s symptoms. Additionally, our findings indicate that allergy to spirulina is not commonly reported or diagnosed. However, most of the described cases (four of five) regarding allergy to spirulina according to WAO Anaphylaxis Guidance 2020 were classified as anaphylaxis. Furthermore, it is noteworthy that spirulina also possesses antiallergic properties, as evidenced by research studies. Our article delves into both the allergic and antiallergic potential of spirulina.
摘要：
目前,蓝绿色微藻螺旋藻（节旋藻）的消费量有所增加，占世界微藻总产量的99.5%。主要作为膳食补充剂出售，它也被纳入零食中，意大利面,饼干,和面包。由于它的营养丰富，螺旋藻具有多种潜在的应用。已经对螺旋藻的健康益处进行了广泛的研究，但是它在过敏方面的安全性受到的关注有限。因此,为了弥补这种知识赤字，这篇综述旨在评估螺旋藻的过敏和抗过敏潜力。在PubMed和Scopus数据库中使用与过敏相关的单词，我们试图检测对螺旋藻过敏的论文。总共确认了128条记录,其中49人被筛选。最终,在这次审查中,我们分析了四个案例研究，包括总共五名对螺旋藻过敏的患者。我们根据世界过敏组织（WAO）2020年过敏反应指南评估了过敏反应的严重程度，该指南根据患者的症状从轻度（2级）到重度（4级）不等。此外,我们的研究结果表明，对螺旋藻过敏并不常见。然而,根据WAO过敏反应指南2020,大多数描述的螺旋藻过敏病例(5例中的4例)被归类为过敏反应.此外，值得注意的是，螺旋藻还具有抗过敏特性，研究证明了这一点。我们的文章深入研究了螺旋藻的过敏和抗过敏潜力。
