PDF(Pubmed)
Abstract：
Background: Accurate prenatal diagnosis of cleft lip and palate is essential to discuss severity prediction, perform appropriate parental counseling, and, at last, establish long-term treatment planning. The aim of this systematic review was to analyze the accuracy of various imaging techniques for the prenatal diagnosis of cleft lip and palate, assess the pregnancy phase for orofacial clefts diagnosis, and study the different cleft types in terms of diagnostic methods, timing, and predictability. Methods: A search of the PubMed, EMBASE, Scopus, and Web of Science databases was conducted to identify potentially relevant studies published until January 2024. The quality of the selected articles was assessed using the Newcastle-Ottawa scale for methodological quality assessment of cohort studies and the QUADAS-2 scale for diagnostic test studies. Results: A total of 18 studies met the eligibility criteria and were included in the review. The findings of this review indicate that the majority of studies showed improved diagnostic accuracy when supplementary techniques, such as 3D ultrasound or magnetic resonance imaging, were added to 2D ultrasound. Conclusions: The implementation of magnetic resonance imaging as a standard procedure could significantly improve the precision of diagnosing cleft lip and palate. Therefore, the diagnostic technique used will play a crucial role in the accuracy of the diagnosis.
摘要：
背景：唇腭裂的准确产前诊断对于讨论严重程度预测至关重要。进行适当的父母咨询，and,最后,制定长期治疗计划。本系统综述旨在分析各种影像技术在唇腭裂产前诊断中的准确性,评估妊娠阶段的口面裂痕诊断，从诊断方法的角度研究不同的裂隙类型，定时,和可预测性。方法：搜索PubMed，EMBASE,Scopus,并进行了WebofScience数据库，以确定直到2024年1月发表的潜在相关研究。所选文章的质量使用纽卡斯尔-渥太华量表进行队列研究的方法学质量评估，并使用QUADAS-2量表进行诊断测试研究。结果：共有18项研究符合资格标准，并被纳入审查。这篇综述的结果表明，大多数研究表明，当补充技术时，诊断准确性有所提高。如3D超声或磁共振成像，被添加到二维超声。结论：将磁共振成像作为标准程序，可以明显提高唇腭裂的诊断精度。因此,所使用的诊断技术将在诊断的准确性中起关键作用。
