Abstract：
Mycotoxins are secondary metabolites produced by fungi and identified as contaminants in animal feed. They have potentially harmful effects, including carcinogenicity, mutagenicity, and repro-toxicity in animals and humans. As a result of climate change, there is the potential for a change in the prevalence and concentration of mycotoxins in animal feed components. This necessitates an assessment of the present and emerging threats to the food supply chain from mycotoxins. This systematic review and meta-analysis study synthesised studies on mycotoxin contamination and prevalence in cattle feed components. The studies were collected from scientific databases Web of Knowledge, Scopus, and Embase between 2011 and 2022. The meta-analysis synthesised 97 studies on the prevalence and the concentration of aflatoxins, ochratoxin A, deoxynivalenol, zearalenone, fumonisin and T-2/HT-2 toxins in feed components. Aflatoxin was highly prevalent (59 %), with a concentration of 2.58-3.92 μg kg-1 in feed components. Ochratoxin A had a global prevalence of 31 % with a concentration of 5.56-12.41 μg kg-1. Deoxynivalenol had a global concentration of 233.17-327.73 μg kg-1 and a prevalence of 74 %. Zearalenone had a prevalence of 70 % and a concentration of 42.47-66.19 μg kg-1. The concentration and prevalence of fumonisins was 232.19-393.07 μg kg-1 and 65 %, respectively. The prevalence and concentration of T-2/HT-2 toxins were 45 % and 23.54-35.12 μg kg-1, respectively. The synthesised concentration of the mycotoxins in the overall feed components was lower than the regulated and guidance values set by the European Union. However, in a few cases, the 95th percentile exceeded these concentration values due to high levels of uncertainty attributed to lower sample size, and thus, need to be considered while conducting risk assessments. The study highlights climates and regions likely to be conducive to the emergence of mycotoxin risk, especially considering the potential influences of climate change.
摘要：
霉菌毒素是由真菌产生的次级代谢产物，被鉴定为动物饲料中的污染物。它们有潜在的有害影响，包括致癌性，致突变性,以及对动物和人类的复制毒性。由于气候变化,动物饲料成分中霉菌毒素的流行率和浓度有可能发生变化。这需要评估霉菌毒素对食品供应链的当前和新出现的威胁。这项系统综述和荟萃分析研究综合了有关牛饲料成分中霉菌毒素污染和患病率的研究。这些研究是从科学数据库WebofKnowledge中收集的，Scopus,和Embase在2011年至2022年之间。荟萃分析综合了97项关于黄曲霉毒素患病率和浓度的研究，曲霉毒素A,脱氧雪腐镰刀菌烯醇,玉米赤霉烯酮,饲料成分中的伏马菌素和T-2/HT-2毒素。黄曲霉毒素非常普遍(59%)，饲料成分中浓度为2.58-3.92μgkg-1。曲霉毒素A的全球患病率为31％，浓度为5.56-12.41μgkg-1。脱氧雪腐镰刀菌烯醇的全球浓度为233.17-327.73μgkg-1，患病率为74％。玉米赤霉烯酮的患病率为70％，浓度为42.47-66.19μgkg-1。伏马菌素的浓度和患病率为232.19-393.07μgkg-1和65％，分别。T-2/HT-2毒素的患病率和浓度分别为45％和23.54-35.12μgkg-1。整个饲料成分中霉菌毒素的合成浓度低于欧盟设定的规定和指导值。然而,在少数情况下，由于较低的样本量导致的高度不确定性，第95百分位数超过了这些浓度值，因此，在进行风险评估时需要考虑。该研究强调了可能有利于霉菌毒素风险出现的气候和地区，特别是考虑到气候变化的潜在影响。
