PDF(Pubmed)
Abstract：
BACKGROUND: Transverse spinal cord infarction (SCI) is rare but highly disabling. Aortic thrombosis was described as one of the most common etiologies. Thromboembolic complications associated with intravenous immunoglobulin (IVIG) have been reported.
METHODS: A previously well, 64-year-old man who was given the treatment of IVIG (0.4 g/kg/d for 5 days) for exfoliative dermatitis 2 weeks before, progressively developed flaccid paraplegia of lower extremities, loss of all sensations below T3 level and urinary incontinence within 50 minutes.
METHODS: A diagnosis of SCI and pulmonary embolism was made. IVIG was considered the possible cause.
METHODS: Anticoagulation treatment and continuous rehabilitation were administered.
RESULTS: The neurologic deficiency of the patient was partially improved at the 3-year follow-up.
CONCLUSIONS: The rapid development of severe deficits within 4 hours mostly contributes to the diagnosis of SCI. Heightened awareness of possible thrombotic events is encouraged for a month-long period following IVIG therapy.
METHODS: A previously well, 64-year-old man who was given the treatment of IVIG (0.4 g/kg/d for 5 days) for exfoliative dermatitis 2 weeks before, progressively developed flaccid paraplegia of lower extremities, loss of all sensations below T3 level and urinary incontinence within 50 minutes.
METHODS: A diagnosis of SCI and pulmonary embolism was made. IVIG was considered the possible cause.
METHODS: Anticoagulation treatment and continuous rehabilitation were administered.
RESULTS: The neurologic deficiency of the patient was partially improved at the 3-year follow-up.
CONCLUSIONS: The rapid development of severe deficits within 4 hours mostly contributes to the diagnosis of SCI. Heightened awareness of possible thrombotic events is encouraged for a month-long period following IVIG therapy.
摘要：
背景：横向脊髓梗死（SCI）很少见，但严重致残。主动脉血栓形成被描述为最常见的病因之一。已经报道了与静脉内免疫球蛋白（IVIG）相关的血栓栓塞并发症。
方法：A以前很好，64岁男性，在2周前给予IVIG（0.4g/kg/d，持续5天）治疗剥脱性皮炎，逐渐发展的下肢弛缓性截瘫，在50分钟内，所有T3水平以下的感觉丧失和尿失禁。
方法：诊断为SCI和肺栓塞。IVIG被认为是可能的原因。
方法：抗凝治疗和持续康复治疗。
结果：患者的神经缺陷在3年的随访中得到部分改善。
结论：4小时内严重缺陷的快速发展主要有助于SCI的诊断。在IVIG治疗后的一个月内，鼓励提高对可能的血栓事件的认识。
方法：A以前很好，64岁男性，在2周前给予IVIG（0.4g/kg/d，持续5天）治疗剥脱性皮炎，逐渐发展的下肢弛缓性截瘫，在50分钟内，所有T3水平以下的感觉丧失和尿失禁。
方法：诊断为SCI和肺栓塞。IVIG被认为是可能的原因。
方法：抗凝治疗和持续康复治疗。
结果：患者的神经缺陷在3年的随访中得到部分改善。
结论：4小时内严重缺陷的快速发展主要有助于SCI的诊断。在IVIG治疗后的一个月内，鼓励提高对可能的血栓事件的认识。
