关键词: Latent class linear mixed model Low back pain Natural course Trajectory

来  源:   DOI:10.1097/PR9.0000000000001152   PDF(Pubmed)

Abstract:
UNASSIGNED: Acute low back pain (LBP) is increasingly recognized for its potential recurrent nature and long-term implications.
UNASSIGNED: This community-based inception cohort study aimed to delineate trajectories of acute LBP over one year and investigate associated biopsychosocial variables.
UNASSIGNED: One hundred seventy-six participants with acute LBP were monitored at 5 follow-up time points over 52 weeks. Pain trajectories were identified using a latent class linear mixed model, and their associations with baseline biopsychosocial factors were evaluated through multinomial logistic regression.
UNASSIGNED: Four distinct LBP trajectories were discerned: \"mild/moderate fluctuating pain\" (54.0%), \"delayed recovery by week 52\" (6.2%), \"persistent moderate pain\" (33.0%), and \"moderate/severe fluctuating pain\" (6.8%). Increased baseline pain intensity and history of LBP episodes were significantly linked with less favorable trajectories. Contrary to expectations, psychological variables like stress, anxiety, and depression did not significantly associate with unfavorable trajectories.
UNASSIGNED: This study underscores the heterogeneity of acute LBP\'s course over a year, challenging the conventionally benign perception of the condition. Recognizing these distinct trajectories might enable more tailored, effective clinical interventions for LBP patients. The small sample size of certain trajectories may influence the generalizability of the results.
UNASSIGNED: Acute LBP can manifest in different trajectories, with nearly half of the participants experiencing less favorable trajectories. Baseline pain intensity and previous episodes of LBP emerged as key factors, whereas psychological variables had no discernible influence. Recognition of these trajectories may be necessary for improved patient management and targeted interventions.
摘要:
急性下腰痛(LBP)因其潜在的复发性和长期影响而日益受到认可。
这项基于社区的初始队列研究旨在描绘急性LBP在一年内的轨迹,并调查相关的生物心理社会变量。
在52周内的5个随访时间点监测了一百七十六名急性LBP参与者。使用潜在类线性混合模型识别疼痛轨迹,通过多项logistic回归评估其与基线生物心理社会因素的关联.
识别出四种不同的LBP轨迹:“轻度/中度波动疼痛”(54.0%),“到第52周延迟复苏”(6.2%),“持续性中度疼痛”(33.0%),和“中度/重度波动疼痛”(6.8%)。基线疼痛强度和LBP发作史的增加与不利的轨迹显着相关。与预期相反,心理变量,如压力,焦虑,抑郁与不利的轨迹没有显着关联。
这项研究强调了一年来急性LBP病程的异质性,挑战传统上对病情的良性看法。认识到这些不同的轨迹可能会更有针对性,LBP患者的有效临床干预措施。某些轨迹的小样本量可能会影响结果的泛化性。
急性LBP可以表现为不同的轨迹,近一半的参与者经历了不太有利的轨迹。基线疼痛强度和先前的LBP发作是关键因素,而心理变量没有明显的影响。这些轨迹的识别对于改善患者管理和有针对性的干预可能是必要的。
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