PDF(Pubmed)
Abstract：
Hypokalemic periodic paralysis (HPP) is an uncommon condition resulting from channelopathy, impacting skeletal muscles. It is distinguished by episodes of sudden and temporary muscle weakness alongside low potassium levels. The normalization of potassium resolves the associated paralysis. Most of these cases are hereditary. Few cases are acquired and are associated with an etiology related to endocrine disorders (e.g., thyrotoxicosis, hyperaldosteronism, and hypercortisolism). It is characterized by acute flaccid paralysis, usually of the ascending type, affecting the proximal region more than the distal region. Herein, we report the case of a 29-year-old male who instead of the ascending type presented with descending-type acute flaccid paralysis. Potassium level at presentation was 1.7 mEq/L. The patient was managed with parenteral and oral potassium supplementation, after which the weakness was completely resolved.
摘要：
低钾性周期性麻痹（HPP）是一种罕见的疾病，由通道病引起，影响骨骼肌。它的特点是突然和暂时的肌肉无力和低钾水平的发作。钾的正常化解决了相关的瘫痪。这些病例大多是遗传的。很少有病例是获得性的，并且与内分泌紊乱相关的病因相关(例如，甲状腺毒症,醛固酮增多症,和皮质醇增多症）。它的特点是急性弛缓性麻痹,通常是上升型的，对近端区域的影响大于对远端区域的影响。在这里，我们报告了一例29岁的男性，他不是上升型，而是下降型急性弛缓性麻痹。展示时的钾水平为1.7mEq/L。患者接受了肠胃外和口服补钾，之后，弱点得到了彻底解决。
