PDF(Pubmed)
Abstract：
Applying the concept of a \"natural history\" to hereditary colorectal cancer is an interesting exercise because the way the syndromes are approached has changed so drastically. However, the exercise is instructive as it forces us to think in depth about where we are, where we have been, and, most helpfully, about where we may be going. In this article the diagnosis, along with endoscopic and surgical management of hereditary colorectal cancer are discussed in the context of their history and the changes in genomics and technology that have occurred over the last one hundred years.
摘要：
将“自然史”的概念应用于遗传性结直肠癌是一个有趣的练习，因为治疗综合征的方式发生了巨大的变化。然而,这个练习很有启发性，因为它迫使我们深入思考我们在哪里，我们去过的地方，and,最有帮助的,我们要去哪里.在这篇文章中的诊断，随着遗传性结直肠癌的内镜和外科治疗在其历史的背景下讨论和基因组学和技术的变化，在过去的一百年。
