关键词: Allium jesdianum anti-bacterial anti-fungal microorganism mouthwash

来  源:   DOI:10.4103/jfmpc.jfmpc_855_23   PDF(Pubmed)

Abstract:
UNASSIGNED: Due to the increasing resistance of bacteria to antibiotics and anti-bacterial compounds in plants, Allium jesdianum Boiss plant extract can be used in mouthwash compounds with its anti-microbial activity.
UNASSIGNED: The anti-bacterial and anti-fungal activity of A. jesdianum mouthwash was investigated on Streptococcus mutans, Streptococcus sanguis, S. salivarius and Candida albicans, and Candida tropicalis. To analyse the anti-microbial effect of this mouthwash, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined by the broth microdilution method.
UNASSIGNED: The average MIC and MBC of A. jesdianum mouthwash for S. mutans were 1.56 and 3.12 (mg/ml), respectively, for S. salivarius, 0.25 and 0.65 (mg/ml), and for S. sanguis, respectively, 0.25 and 0.65 (mg/ml). The highest MIC and MBC values were for S. mutans, and the MIC and MBC values were equal for S. sanguis and S. salivarius. Average MIC and MBC were determined as 2.41 and 4.16 (mg/ml) for C. albicans and 2.34 and 5.72 (mg/ml) for C. tropicalis, respectively. MIC values of mouthwash were higher for C. albicans and MBC values for C. tropicalis.
UNASSIGNED: Our results showed a promising anti-fungal-anti-bacterial effect of A. jesdianum extract. A. jesdianum extract may be used as an alternative to chemical mouthwashes.
摘要:
由于植物中细菌对抗生素和抗菌化合物的抵抗力不断增强,葱花植物提取物具有抗微生物活性,可用于漱口水化合物。
研究了A.jesdianum漱口水对变形链球菌的抗菌和抗真菌活性,血链球菌,唾液和白色念珠菌,和热带念珠菌.为了分析这种漱口水的抗微生物作用,通过肉汤微量稀释法测定最小抑菌浓度(MIC)和最小杀菌浓度(MBC)。
A.jesdianum漱口水对变形链球菌的平均MIC和MBC分别为1.56和3.12(mg/ml),分别,唾液链球菌,0.25和0.65(mg/ml),对于S.sanguis来说,分别,0.25和0.65(mg/ml)。最高的MIC和MBC值是变形链球菌,血链球菌和唾液链球菌的MIC和MBC值相等。白色念珠菌的平均MIC和MBC分别为2.41和4.16(mg/ml),热带念珠菌的平均MIC和MBC分别为2.34和5.72(mg/ml)。分别。漱口水的MIC值对于白色念珠菌较高,并且MBC值对于热带念珠菌较高。
我们的结果显示A.jesdianum提取物的有希望的抗真菌-抗菌作用。A.jesdianum提取物可以用作化学漱口水的替代品。
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