Abstract：
Nanoparticles (NPs) have been extensively investigated for their potential in nanomedicine. There is a significant level of enthusiasm about the potential of NPs to bring out a transformative impact on modern healthcare. NPs can serve as effective wound dressings or delivery vehicles due to their antibacterial and pro-wound-healing properties. Biopolymer-based NPs can be manufactured using various food-grade biopolymers, such as proteins, polysaccharides, and synthetic polymers, each offering distinct properties suitable for different applications which include collagen, polycaprolactone, chitosan, alginate, and polylactic acid, etc. Their biodegradable and biocompatible nature renders them ideal nanomaterials for applications in wound healing. Additionally, the nanofibers containing biopolymer-based NPs have shown excellent anti-bacterial and wound healing activity like silver NPs. These NPs represent a paradigm shift in wound healing therapies, offering targeted and personalized solutions for enhanced tissue regeneration and accelerated wound closure. The current review focuses on biopolymer NPs with their applications in wound healing.
摘要：
纳米颗粒（NPs）在纳米医学中的潜力已被广泛研究。人们对NPs对现代医疗保健产生变革性影响的潜力抱有很大的热情。由于它们的抗菌和促伤口愈合特性,NP可以用作有效的伤口敷料或递送载体。基于生物聚合物的NP可以使用各种食品级生物聚合物制造，如蛋白质，多糖，和合成聚合物，每个提供不同的属性适合不同的应用，包括胶原蛋白，聚己内酯,壳聚糖,海藻酸盐,和聚乳酸，等。它们的生物可降解和生物相容性使它们成为应用于伤口愈合的理想纳米材料。此外,含有基于生物聚合物的NP的纳米纤维已经显示出优异的抗菌和伤口愈合活性,如银NP。这些NP代表了伤口愈合疗法的范式转变，提供针对性和个性化的解决方案，以增强组织再生和加速伤口闭合。目前的综述集中在生物聚合物NP及其在伤口愈合中的应用。
