Abstract：
BACKGROUND: Sternal cleft (SC), a rare thoracic malformation, is associated with pectus excavatum (PE) in 2.6-5% of cases. It remains unclear if these conditions are congenitally linked or if SC repair triggers PE. To investigate the potential higher frequency of PE in SC cases, we conducted a retrospective study of our SC patients.
METHODS: We assessed PE incidence, progression, and management in SC patients treated at our institute from 2006 to 2022. When available, we collected pre-SC repair CT scan data, calculating the Haller Index (HI) and Correction Index (CI) and compared them to a selected control group.
RESULTS: Among 8 SC patients, 7 had concomitant PE (87.5%), varying in severity. PE management ranged from observation to thoracoplasty, depending on its degree. We observed a significant pre-operative CI difference between SC and control group patients (p < 0.00001). In the last two SC repair cases, we attempted concurrent PE prevention or treatment.
CONCLUSIONS: Our findings suggest an underestimated association between PE and SC in the existing literature. SC patients may exhibit a predisposition to PE from birth, which may become more apparent with growth after SC repair. Consequently, PE prevention or treatment should be considered during SC repair procedures.
METHODS: We assessed PE incidence, progression, and management in SC patients treated at our institute from 2006 to 2022. When available, we collected pre-SC repair CT scan data, calculating the Haller Index (HI) and Correction Index (CI) and compared them to a selected control group.
RESULTS: Among 8 SC patients, 7 had concomitant PE (87.5%), varying in severity. PE management ranged from observation to thoracoplasty, depending on its degree. We observed a significant pre-operative CI difference between SC and control group patients (p < 0.00001). In the last two SC repair cases, we attempted concurrent PE prevention or treatment.
CONCLUSIONS: Our findings suggest an underestimated association between PE and SC in the existing literature. SC patients may exhibit a predisposition to PE from birth, which may become more apparent with growth after SC repair. Consequently, PE prevention or treatment should be considered during SC repair procedures.
摘要：
背景：胸骨裂（SC），罕见的胸部畸形,在2.6-5％的病例中与漏斗胸（PE）相关。目前尚不清楚这些情况是否与先天相关，或者SC修复是否引发PE。为了研究SC病例中潜在的更高频率的PE，我们对SC患者进行了一项回顾性研究.
方法：我们评估了PE发生率，programming,以及2006年至2022年在我们研究所治疗的SC患者的管理。如果可用,我们收集了SC修复前的CT扫描数据，计算哈勒指数（HI）和校正指数（CI），并将它们与选定的对照组进行比较。
结果：在8例SC患者中，7例合并PE（87.5%），严重程度不同。PE管理范围从观察到胸廓成形术，取决于它的程度。我们观察到SC组和对照组患者的术前CI有显著差异(p<0.00001)。在最近两个SC修复案例中，我们尝试同时预防或治疗PE.
结论：我们的研究结果表明，现有文献中PE和SC之间存在低估的关联。SC患者可能从出生起就表现出PE的倾向，随着SC修复后的生长，这可能变得更加明显。因此,在SC修复过程中应考虑PE的预防或治疗。
方法：我们评估了PE发生率，programming,以及2006年至2022年在我们研究所治疗的SC患者的管理。如果可用,我们收集了SC修复前的CT扫描数据，计算哈勒指数（HI）和校正指数（CI），并将它们与选定的对照组进行比较。
结果：在8例SC患者中，7例合并PE（87.5%），严重程度不同。PE管理范围从观察到胸廓成形术，取决于它的程度。我们观察到SC组和对照组患者的术前CI有显著差异(p<0.00001)。在最近两个SC修复案例中，我们尝试同时预防或治疗PE.
结论：我们的研究结果表明，现有文献中PE和SC之间存在低估的关联。SC患者可能从出生起就表现出PE的倾向，随着SC修复后的生长，这可能变得更加明显。因此,在SC修复过程中应考虑PE的预防或治疗。
