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Abstract：
Pseudoangiomatous stromal hyperplasia (PASH) is a benign interstitial hyperplasia of the breast that usually occurs in premenopausal or perimenopausal women. It is usually characterized by localized lesions or clear boundary masses, and diffuse double breast enlargement is rare. PASH is considered a hormone-dependent disease that is commonly progesterone related. There are no imaging characteristics, and both benign and suspicious malignant signs can be seen. The definitive diagnosis of PASH depends on a pathological diagnosis, and it is necessary to be vigilant in distinguishing between benign and malignant tumors with similar breast histopathology. Here, we report the case of a 23-year-old multipara patient with bilateral diffuse pseudoangiomatous stromal hyperplasia of the breast during pregnancy who presented with macromastia and reviewed the literature to further understand the clinical features, pathological diagnosis, differential diagnosis, treatment and prognosis of pseudoangiomatous stromal hyperplasia of the breast.
摘要：
假性血管瘤性间质增生（PASH）是一种良性的乳腺间质增生，通常发生在绝经前或围绝经期妇女中。它通常以局部病变或清晰的边界肿块为特征，弥漫性双乳房增大很少见。PASH被认为是激素依赖性疾病，通常与孕酮有关。没有成像特征，可以看到良性和可疑的恶性症状。PASH的最终诊断取决于病理诊断，在乳腺组织病理学相似的良性和恶性肿瘤之间的区别是必要的。这里,我们报告了一例23岁的多层患者，在怀孕期间患有双侧弥漫性假性血管瘤性乳腺间质增生，并回顾了文献以进一步了解其临床特征。病理诊断,鉴别诊断,乳腺假性血管瘤性间质增生的治疗和预后。
