关键词: Camellia sinensis Catechin Eye diseases Green tea Integrative medicine Ocular diseases Traditional Persian medicine

来  源:   DOI:10.1016/j.heliyon.2024.e28829   PDF(Pubmed)

Abstract:
This review aims to evaluate the therapeutic potential of green tea (GT), scientifically named Camellia sinensis, in treating eye diseases. We provide an overview of the ingredients and traditional use of Camellia sinensis, followed by a detailed discussion of its therapeutic uses in various eye diseases, including ocular surface diseases (allergic diseases, dry eye, pterygium, and infections), cataract, glaucoma, uveitis, retinal diseases, and optic nerve diseases. The pharmacologic activities related to ocular diseases, such as anti-vascular endothelial growth factor, aldose reductase inhibitor activity, anti-bacterial, anti-inflammatory, and antioxidant effects are also explored in this review. The dose and route of administration of GT in various studies are discussed. Safety issues related to the use of GT, such as the side effects associated with high doses and long-term use, are also addressed. The review highlights the potential of GT as a natural therapeutic agent for a variety of ocular diseases. Its various pharmacologic activities make it a promising treatment option. However, more well-designed studies are needed to determine the optimal dose and route of administration and to assess its long-term safety and efficacy. Overall, GT appears to be a promising adjunct therapy for various ocular diseases.
摘要:
这篇综述旨在评估绿茶(GT)的治疗潜力,科学上命名为山茶,治疗眼部疾病。我们概述了山茶的成分和传统用途,随后详细讨论了其在各种眼部疾病中的治疗用途,包括眼表疾病(过敏性疾病,干眼症,翼状胬肉,和感染),白内障,青光眼,葡萄膜炎,视网膜疾病,和视神经疾病。与眼部疾病相关的药理活性,如抗血管内皮生长因子,醛糖还原酶抑制剂活性,抗菌,抗炎,和抗氧化作用也在这篇综述中进行了探讨。讨论了各种研究中GT的剂量和给药途径。与GT使用相关的安全问题,例如与高剂量和长期使用相关的副作用,也解决了。该综述强调了GT作为多种眼部疾病的天然治疗剂的潜力。其各种药理活性使其成为有希望的治疗选择。然而,需要更精心设计的研究来确定最佳给药剂量和给药途径,并评估其长期安全性和有效性.总的来说,GT似乎是各种眼部疾病的有希望的辅助疗法。
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