关键词: atopic dermatitis drug-induced steatohepatitis steatohepatitis topical corticosteroids

来  源:   DOI:10.2169/internalmedicine.3439-23

Abstract:
Atopic dermatitis is common in children and often treated with topical corticosteroids (TCs). A boy in his late teens who had been using TCs for atopic dermatitis was diagnosed with liver damage during a health checkup. A medical examination revealed severe steatotic liver disease and elevated liver enzyme levels despite the absence of typical symptoms such as central obesity. After discontinuation of TCs, an improvement in liver enzyme levels was observed, leading to the diagnosis of drug-induced steatohepatitis. This case underscores the potential liver risks associated with prolonged TC use in children, highlighting the need for parental education.
摘要:
特应性皮炎在儿童中很常见,通常使用外用皮质类固醇(TC)治疗。一个十几岁的男孩一直在使用TC治疗特应性皮炎,在健康检查中被诊断为肝损伤。尽管没有典型的症状,例如中心性肥胖,但医学检查显示严重的脂肪变性肝病和肝酶水平升高。停止TC后,观察到肝酶水平的改善,导致药物诱导的脂肪性肝炎的诊断。该病例强调了儿童长期使用TC的潜在肝脏风险,强调父母教育的必要性。
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