Abstract：
Identify the most recent and significant evidence regarding the ovulation trigger within the framework of a multicycle approach through DuoStim, providing valuable insights for improving treatment strategies in patients with a poor prognosis.
The trigger method plays a pivotal role in optimizing in-vitro fertilization (IVF) stimulation, influencing oocyte retrieval and maturation rates, as well as follicle recruitment in consecutive ovarian stimulations such as double stimulation. Decision-making involves multiple factors and, while guidelines exist for conventional stimulation, specific recommendations for the multicycle approach are not well established.
The different methods for inducing oocyte maturation underscore the need for personalization of IVF protocols. The GnRH agonist trigger induces rapid luteolysis and establishes favorable hormonal conditions that do not adversely affect the recruitment of consecutive follicular waves in the context of DuoStim. It serves as a valid alternative to hCG in freeze-all cycles. This strategy might enhance the safety and flexibility of ovarian stimulations with no impact on oocyte competence and IVF efficacy.
The trigger method plays a pivotal role in optimizing in-vitro fertilization (IVF) stimulation, influencing oocyte retrieval and maturation rates, as well as follicle recruitment in consecutive ovarian stimulations such as double stimulation. Decision-making involves multiple factors and, while guidelines exist for conventional stimulation, specific recommendations for the multicycle approach are not well established.
The different methods for inducing oocyte maturation underscore the need for personalization of IVF protocols. The GnRH agonist trigger induces rapid luteolysis and establishes favorable hormonal conditions that do not adversely affect the recruitment of consecutive follicular waves in the context of DuoStim. It serves as a valid alternative to hCG in freeze-all cycles. This strategy might enhance the safety and flexibility of ovarian stimulations with no impact on oocyte competence and IVF efficacy.
摘要：
目的：在通过DuoStim的多周期方法的框架内，确定有关排卵触发的最新和重要证据，为改善预后不良患者的治疗策略提供有价值的见解。
结果：触发方法在优化体外受精（IVF）刺激中起着关键作用，影响卵母细胞提取和成熟率，以及连续卵巢刺激中的卵泡募集，如双重刺激。决策涉及多个因素,虽然有常规刺激的指导方针，关于多周期方法的具体建议还没有得到很好的确立。
结论：诱导卵母细胞成熟的不同方法强调了IVF方案个性化的必要性。在DuoStim的背景下，GnRH激动剂触发器诱导快速黄体溶解并建立有利的激素条件，不会对连续卵泡波的募集产生不利影响。它在冷冻-所有循环中作为hCG的有效替代品。该策略可能会增强卵巢刺激的安全性和灵活性，而不会影响卵母细胞能力和IVF疗效。
结果：触发方法在优化体外受精（IVF）刺激中起着关键作用，影响卵母细胞提取和成熟率，以及连续卵巢刺激中的卵泡募集，如双重刺激。决策涉及多个因素,虽然有常规刺激的指导方针，关于多周期方法的具体建议还没有得到很好的确立。
结论：诱导卵母细胞成熟的不同方法强调了IVF方案个性化的必要性。在DuoStim的背景下，GnRH激动剂触发器诱导快速黄体溶解并建立有利的激素条件，不会对连续卵泡波的募集产生不利影响。它在冷冻-所有循环中作为hCG的有效替代品。该策略可能会增强卵巢刺激的安全性和灵活性，而不会影响卵母细胞能力和IVF疗效。
