关键词: EHPSS feline portal anatomy portal vein portosystemic shunt shunt anatomy

来  源:   DOI:10.1111/vru.13363

Abstract:
The prevalence of anatomical-based subtypes of feline congenital extrahepatic portosystemic shunts (EHPSS) has not been completely elucidated. The goal of this study was to use CT angiography to create an anatomical-based nomenclature system for feline congenital EHPSS. Additionally, subjective portal perfusion scores were generated to determine if intrinsic portal vein development was associated with different shunt conformations or patient age at the time of CT. The SVSTS and VIRIES list services were used to recruit cases. Data collected included patient DOB, gender, breed, weight, CT date, and reported diagnosis. Shunts were classified based upon (1) the shunt portal vessel(s) of origin, (2) the shunt systemic vessel(s) of insertion, and (3) any substantial portal vessels contributing to the shunt. Additionally, hepatic portal perfusion was subjectively scored between 1 (poor/none) and 5 (good/normal) based on the caliber of the intrahepatic PVs. A total of 264 CT scans were submitted from 29 institutions. Due to exclusion criteria, 33 (13%) were removed, leaving 231 CT scans to be included. Twenty-five different EHPSS anatomies were identified with five classifications accounting for 78% of all shunts (LGP [53%], LGC-post [11%], LCG [7%], LGC-pre [4%], and PC [4%]). Shunt origin involved the left gastric vein in 75% of the described classifications. Significant differences were identified among the five most common shunt types with respect to age at the time of CT scan (P = .002), breed (P < .001), and subjective portal perfusion score (P < .001). This refined anatomical classification system for feline EHPSS may enable improved understanding, treatment comparisons, and outcome prediction for cats with these anomalies.
摘要:
猫先天性肝外门体分流术(EHPSS)的基于解剖学的亚型的患病率尚未完全阐明。这项研究的目的是使用CT血管造影为猫科动物先天性EHPSS创建基于解剖学的命名系统。此外,产生主观门静脉灌注评分,以确定内在门静脉发育是否与CT时的不同分流构象或患者年龄相关.SVSTS和VIRIES列表服务用于招募案件。收集的数据包括患者DOB,性别,品种,体重,CT日期,并报告诊断。分流根据(1)分流门脉血管的起源进行分类,(2)插入的分流全身血管,和(3)有助于分流的任何实质性门静脉。此外,根据肝内PV的口径,肝门灌注主观评分在1(差/无)和5(良好/正常)之间。共有来自29个机构的264次CT扫描。由于排除标准,33(13%)被删除,留下231个CT扫描。确定了25种不同的EHPSS解剖结构,其中5种分类占所有分流的78%(LGP[53%],LGC-post[11%],LCG[7%],LGC-pre[4%],和PC[4%])。分流术的起源涉及所描述的分类的75%的胃左静脉。在CT扫描时,五种最常见的分流类型之间的年龄存在显着差异(P=0.002),品种(P<.001),和主观门静脉灌注评分(P<0.001)。这种用于猫科动物EHPSS的精细解剖分类系统可以提高理解,治疗比较,以及具有这些异常的猫的结果预测。
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