关键词: Chronic wounds Clinical study Platelet-poorplasma Platelet-rich plasma Skin

来  源:   DOI:10.1016/j.reth.2024.02.011   PDF(Pubmed)

Abstract:
Skin injuries are a global healthcare problem. Chronic ulcers do not heal in a timely fashion, so it is essential to help the body with skin repair. There are some treatments that have been applied to chronic ulcers. One of these treatments is growth factor (GF) therapy. Platelet-rich plasma (PRP) and Platelet-poor plasma (PPP) are two types of plasma derivatives containing many GFs important for wound healing. Several works have reported their application in wound healing and tissue regeneration. The use of autologous PRP is now an adequate alternative in regenerative medicine. It was also demonstrated that PPP is a hemostatic agent for wounds. This review has studied the latest clinical studies, which have applied PRP and PPP to patients with chronic wounds.
摘要:
皮肤损伤是一个全球性的医疗保健问题。慢性溃疡不能及时愈合,所以帮助身体与皮肤修复是必不可少的。有一些治疗方法已应用于慢性溃疡。这些治疗之一是生长因子(GF)治疗。富血小板血浆(PRP)和贫血小板血浆(PPP)是两种类型的血浆衍生物,含有许多对伤口愈合重要的GF。一些工作已经报道了它们在伤口愈合和组织再生中的应用。自体PRP的使用现在是再生医学中的适当替代方案。还证明了PPP是用于伤口的止血剂。这篇综述研究了最新的临床研究,已将PRP和PPP应用于慢性伤口患者。
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