PDF(Pubmed)
Abstract：
Background The research delves into the intricate relationship between periodontal health and specific blood biomarkers in pregnant women during their second trimester. It specifically focuses on the levels of interleukin-6 (IL-6), lactate dehydrogenase (LDH), and C-reactive protein (CRP) in those suffering from chronic periodontitis compared to healthy controls. Methodology A detailed approach was taken involving 60 pregnant women categorized into two groups based on the presence or absence of chronic periodontitis. Out of 60 pregnant women, 30 had chronic periodontitis, while the other 30 served as controls selected from the regular patient population of the college. The study utilized blood sample analysis and advanced statistical tools for data analysis, ensuring precise and reliable results. Levels of IL-6, LDH, and CRP in those suffering from chronic periodontitis compared to healthy controls were checked. Results The findings revealed a notable variance in IL-6, LDH, and CRP levels between the two groups. Women with chronic periodontitis exhibited significantly higher levels of these biomarkers. The statistical analysis reinforced the validity of these differences, highlighting their significance. Conclusions The study underscored a clear link between higher levels of IL-6, LDH, and CRP and the presence of chronic periodontitis in pregnant women. These biomarkers emerge as potential indicators for early detection and monitoring of periodontal health in this demographic.
摘要：
背景这项研究探讨了妊娠中期孕妇牙周健康与特定血液生物标志物之间的复杂关系。它特别关注白细胞介素-6（IL-6）的水平，乳酸脱氢酶（LDH），与健康对照组相比，患有慢性牙周炎的患者的C反应蛋白（CRP）。方法采用详细的方法，根据是否存在慢性牙周炎，将60名孕妇分为两组。在60名孕妇中，30人患有慢性牙周炎，而其他30人作为对照组，从学院的常规患者人群中选择。该研究利用血液样本分析和先进的统计工具进行数据分析，确保准确可靠的结果。IL-6、LDH、与健康对照组相比，检查了患有慢性牙周炎的患者的CRP。结果发现IL-6、LDH、两组CRP水平比较。患有慢性牙周炎的女性表现出明显更高水平的这些生物标志物。统计分析加强了这些差异的有效性，强调其意义。结论该研究强调了高水平的IL-6，LDH，和CRP和孕妇慢性牙周炎的存在。这些生物标志物作为早期检测和监测牙周健康的潜在指标出现。
