关键词: Antiphospholipid antibody syndrome (APLA) multi-disciplinary management posterior reversible encephalopathy syndrome (PRES) postpartum paraplegia pre-eclampsia

来  源:   DOI:10.4103/jpbs.jpbs_915_23   PDF(Pubmed)

Abstract:
In this case report, a 27-year-old woman who had pre-eclampsia in the past and had a cesarean section as a result of the condition presents with an uncommon and difficult form of postpartum paraplegia. She experienced bilateral lower limb paralysis and urine incontinence soon after the surgery, which quickly led to unconsciousness and required mechanical ventilator support and intensive care treatment. Comprehensive diagnostic testing, which included magnetic resonance imaging scans of the brain and spinal cord, identified signs typical of \"Posterior Reversible Encephalopathy Syndrome (PRES)\" and spinal cord infarction affecting segments C3 to D2. \"Antiphospholipid Antibody Syndrome (APLA)\" was identified by laboratory testing, highlighting the significance of taking a thorough approach to comprehending this uncommon clinical condition. Treatment included anticoagulant therapy, high-dose steroid therapy, and antihypertensive drugs, emphasizing the crucial importance of inter-disciplinary care in handling such complex situations. Even if the patient\'s symptoms have partially improved, their condition is still being closely monitored in the intensive care unit. In the context of postpartum neurological problems and the complex interplay between pre-eclampsia, spinal cord infarction, and related clinical symptoms, this case emphasizes the need for increased awareness and prompt management.
摘要:
在这个案例报告中,一名27岁的妇女过去曾患有先兆子痫,并因这种情况而进行了剖宫产,其产后截瘫的形式并不常见且困难。手术后不久,她出现了双侧下肢瘫痪和尿失禁,这很快导致意识不清,需要机械呼吸机支持和重症监护治疗。全面的诊断测试,其中包括大脑和脊髓的磁共振成像扫描,确定典型的“后部可逆性脑病综合征(PRES)”和脊髓梗塞影响C3至D2段的征象。“抗磷脂抗体综合征(APLA)”通过实验室测试确定,强调采取彻底的方法来理解这种罕见的临床状况的重要性。治疗包括抗凝治疗,大剂量类固醇治疗,和抗高血压药物,强调跨学科关怀在处理这种复杂情况中的至关重要性。即使病人的症状有部分改善,重症监护室仍在密切监测他们的病情。在产后神经问题和子痫前期之间复杂的相互作用的背景下,脊髓梗塞,和相关的临床症状,这个案例强调了提高认识和迅速管理的必要性。
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