PDF(Pubmed)
Abstract：
There are plenty of benign lesions that can result in swelling of the mandible, and these can be classified as odontogenic and non-odontogenic lesions. Among the categories of odontogenic lesion, ameloblastoma is the most occurring lesion that takes origin from the epithelial cellular elements and dental tissues in their different stages of development. Ameloblastoma is the most serious odontogenic neoplasm due to its prevalence and clinical characteristics. Ameloblastoma is a broad class which encompasses 80% of solid multicystic type of ameloblastoma with unicystic ameloblastoma (UA) variant included as vital clinicopathological form claiming the rest 20% along with peripheral ameloblastoma variant. UA refers to cystic lesions that seem like jaw cysts clinically, radiographically, or grossly but are lined by typical ameloblastomatous epithelium, with or without luminal and/or mural tumor development, on histologic investigation. Around 5-15% of all ameloblastic lesions do not have a propensity to metastasis, and this is UA. Unicystic mural form, although slow growing overall, is very invasive locally and has a high recurrence rate. As UA tumors show very close features with dentigerous cyst, a very sharp differential diagnosis protocol need to be executed to exclude the other unicystic odontogenic lesions considering the clinical, radiological, and biological characteristics along with proper follow-up and seeing any recurrence of the lesion taking place. Here, we report the case of a twenty-one year male patient with UA of the mandible and review of the literature.
摘要：
有很多良性病变会导致下颌骨肿胀，这些可以分为牙源性和非牙源性病变。在牙源性病变的类别中，成釉细胞瘤是发生最多的病变，起源于上皮细胞元素和牙齿组织的不同发育阶段。成釉细胞瘤由于其患病率和临床特征而成为最严重的牙源性肿瘤。成釉细胞瘤是一个广泛的类别，包括80％的固体多囊性成釉细胞瘤，其中单囊性成釉细胞瘤（UA）变体作为重要的临床病理形式，其余20％与周围成釉细胞瘤变体一起。UA是指临床上看起来像颌骨囊肿的囊性病变，射线照相，或大致但由典型的成釉细胞上皮排列，有或没有腔和/或壁肿瘤的发展，组织学调查。大约5-15%的成釉细胞病变没有转移倾向，这是UA.单一的壁画形式，虽然总体增长缓慢，局部侵入性强，复发率高。由于UA肿瘤表现出非常接近的特征与牙质囊肿，考虑到临床，需要执行一个非常尖锐的鉴别诊断方案来排除其他单囊性牙源性病变，放射学,和生物学特征以及适当的随访，并观察病变的任何复发。这里,我们报告一例21岁的男性下颌骨UA患者并进行文献复习。
