PDF(Pubmed)
Abstract：
While most children with epilepsy find their seizures manageable through medication, some continue to experience seizures despite trying multiple drugs. Failure of medical treatment often becomes apparent early on, and for these cases, it is advisable to seek further treatment options at a specialized epilepsy center. Such centers offer additional treatments like epilepsy surgery, vagus nerve stimulation, and ketogenic diets. There is no universal definition for what constitutes \"medically intractable\" epilepsy. A proposal by a task force from the International League Against Epilepsy suggests that drug-resistant epilepsy could be defined as the inability to control seizures even after two adequate treatment attempts with well-chosen and tolerated medications, either alone or in combination. In this review, the authors discussed the management of intractable epilepsy in children.
摘要：
虽然大多数癫痫患儿发现他们的癫痫发作可以通过药物治疗来控制，尽管尝试了多种药物，一些人仍继续癫痫发作。医疗失败往往在早期就变得明显，对于这些情况，建议在专门的癫痫中心寻求进一步的治疗选择.这些中心提供额外的治疗方法，如癫痫手术，迷走神经刺激,和生酮饮食。对于什么构成“医学上难治的”癫痫没有普遍的定义。国际抗癫痫联盟的一个特别工作组的建议表明，耐药性癫痫可以被定义为即使在使用精心选择和耐受的药物进行两次适当的治疗尝试后仍无法控制癫痫发作。单独或组合。在这次审查中,作者讨论了儿童难治性癫痫的治疗方法.
