关键词: Cervical cancer prevention SADC Screening guidelines WHO

Mesh : Humans Uterine Cervical Neoplasms / diagnosis prevention & control Female Early Detection of Cancer Africa, Southern / epidemiology Practice Guidelines as Topic Mass Screening Adult World Health Organization

来  源:   DOI:10.1016/j.jcpo.2024.100477

Abstract:
BACKGROUND: Cervical cancer poses a significant burden, particularly in low-and-middle income countries (LMIC) with limited access to healthcare. High-income countries have made progress in prevention, while LMIC face unacceptably high incidence and mortality rates, often lacking official screening recommendations. We analysed the presence and content of cervical cancer screening guidelines for the secondary prevention of cervical cancer in the Southern African Development Community (SADC) and compared it to the current World Health Organization (WHO) guidelines for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention.
METHODS: A review of national cervical cancer guidelines across the SADC region was conducted. Data was obtained from government websites, international cancer control platforms, and WHO resources. Search terms included \"cervical cancer\" and \"cervical cancer control guidelines\", amongst others. There were no limitations on publication years, and the most recent versions of the guidelines were analysed, regardless of language. Each guideline was assessed for specific screening and treatment recommendations, in relation to the current WHO guidelines. Points were assigned for each data element.
RESULTS: While most countries contributed data to this analysis there was a notable absence of adherence to the WHO guidelines. The most common screening method was naked eye visual inspection. There was a consensus on the age of screening initiation. Most countries recommended treatment by cryotherapy and loop excision.
CONCLUSIONS: Effective cervical cancer screening programmes, guided by evidence-based recommendations, can enhance early intervention and outcomes. This study highlights the need for standardized and evidence-based cervical cancer screening guidelines in the SADC region, to reduce the burden of cervical cancer and improve the health outcomes of women in these areas.
摘要:
背景:宫颈癌带来了巨大的负担,特别是在获得医疗保健的机会有限的中低收入国家(LMIC)。高收入国家在预防方面取得了进展,虽然LMIC面临令人无法接受的高发病率和死亡率,往往缺乏官方的筛选建议。我们分析了南部非洲发展共同体(SADC)宫颈癌二级预防宫颈癌筛查指南的存在和内容,并将其与当前世界卫生组织(WHO)宫颈癌前病变筛查和治疗指南进行了比较。
方法:对SADC地区的国家宫颈癌指南进行了综述。数据来自政府网站,国际癌症控制平台,世卫组织资源。搜索词包括“宫颈癌”和“宫颈癌控制指南”,在其他人中。出版年份没有限制,并分析了最新版本的指南,不管语言。评估每个指南的具体筛查和治疗建议。与目前的世卫组织准则有关。为每个数据元素分配点。
结果:虽然大多数国家为该分析提供了数据,但明显缺乏对WHO指南的遵守。最常见的筛查方法是肉眼目视检查。对筛查开始的年龄有共识。大多数国家建议通过冷冻疗法和环切除术进行治疗。
结论:有效的宫颈癌筛查计划,以循证建议为指导,可以加强早期干预和结果。这项研究强调了在南共体地区建立标准化和循证宫颈癌筛查指南的必要性。减轻宫颈癌的负担,改善这些地区妇女的健康结果。
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