细胞谱系引发中的增强子转换与 eRNA 有关 ,Brg1\ 's AT - hook,和 SWI / SNF 招聘。
关键词: Brg1/Smarca4 EpiSCs MLL3/4 RNAPII SWI/SNF eRNA enhancer mediator (Med1) naive p300/CBP primed
Mesh : Animals Humans Cell Lineage / genetics Chromatin Assembly and Disassembly Chromosomal Proteins, Non-Histone / metabolism genetics DNA Helicases / metabolism genetics Enhancer Elements, Genetic Nuclear Proteins / metabolism genetics Transcription Factors / metabolism genetics
来 源:
DOI:10.1016/j.molcel.2024.03.013
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