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Abstract：
Chronic kidney disease (CKD) represents one of today\'s main public health problems. Serum creatinine measurement and estimation of the glomerular filtration rate (GFR) are the main tools for evaluating renal function. There are several equations to estimate GFR, and CKD-EPI equation (Chronic Kidney Disease - Epidemiology) is the most recommended one. There are still some controversies regarding serum creatinine measurement and GFR estimation, since several factors can interfere in this process. An important recent change was the removal of the correction for race from the equations for estimating GFR, which overestimated kidney function, and consequently delayed the implementation of treatments such as dialysis and kidney transplantation. In this consensus document from the Brazilian Societies of Nephrology and Clinical Pathology and Laboratory Medicine, the main concepts related to the assessment of renal function are reviewed, as well as possible existing controversies and recommendations for estimating GFR in clinical practice.
摘要：
慢性肾脏病(CKD)是当今主要的公共卫生问题之一。血清肌酐测量和肾小球滤过率（GFR）的估计是评估肾功能的主要工具。有几个方程来估计GFR，CKD-EPI方程（慢性肾脏病-流行病学）是最推荐的方程。关于血清肌酐的测量和GFR的估计仍存在一些争议，因为有几个因素会干扰这个过程。最近的一个重要变化是从估计GFR的方程中删除了种族校正，高估了肾功能，并因此推迟了透析和肾移植等治疗方法的实施。在巴西肾脏病学与临床病理学和实验室医学学会的这份共识文件中，回顾了与肾功能评估相关的主要概念，以及临床实践中可能存在的估计GFR的争议和建议。
