PDF(Pubmed)
Abstract：
The auxin response factor (ARF) and auxin/indole-3-acetic acid (Aux/IAA) family of genes are central components of the auxin signaling pathway and play essential roles in plant growth and development. Their large-scale analysis and evolutionary trajectory of origin are currently not known. Here, we identified the corresponding ARF and Aux/IAA family members and performed a large-scale analysis by scanning 406 plant genomes. The results showed that the ARF and Aux/IAA gene families originated from charophytes. The ARF family sequences were more conserved than the Aux/IAA family sequences. Dispersed duplications were the common expansion mode of ARF and Aux/IAA families in bryophytes, ferns, and gymnosperms; however, whole-genome duplication was the common expansion mode of the ARF and Aux/IAA families in basal angiosperms, magnoliids, monocots, and dicots. Expression and regulatory network analyses revealed that the Arabidopsis thaliana ARF and Aux/IAA families responded to multiple hormone, biotic, and abiotic stresses. The APETALA2 and serum response factor-transcription factor gene families were commonly enriched in the upstream and downstream genes of the ARF and Aux/IAA gene families. Our study provides a comprehensive overview of the evolutionary trajectories, structural functions, expansion mechanisms, expression patterns, and regulatory networks of these two gene families.
摘要：
生长素响应因子（ARF）和生长素/吲哚-3-乙酸（Aux/IAA）基因家族是生长素信号通路的核心组成部分，在植物的生长发育中起着至关重要的作用。他们的大规模分析和起源的进化轨迹目前尚不清楚。这里,我们鉴定了相应的ARF和Aux/IAA家族成员,并通过扫描406个植物基因组进行了大规模分析.结果表明，ARF和Aux/IAA基因家族起源于木薯。ARF家族序列比Aux/IAA家族序列更保守。分散的重复是苔藓植物中ARF和Aux/IAA家族的常见扩展模式，蕨类植物,和裸子植物；然而，全基因组复制是基底被子植物ARF和Aux/IAA家族的常见扩增模式，木兰,单子叶植物,还有双子叶.表达和调控网络分析显示拟南芥ARF和Aux/IAA家族对多种激素有反应,生物，和非生物胁迫。APETALA2和血清反应因子-转录因子基因家族通常富集在ARF和Aux/IAA基因家族的上游和下游基因中。我们的研究提供了进化轨迹的全面概述，结构功能，扩展机制，表达模式，以及这两个基因家族的调控网络。
